4AY2
Capturing 5' tri-phosphorylated RNA duplex by RIG-I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROBABLE ATP-DEPENDENT RNA HELICASE DDX58 | polymer | 687 | 78686.8 | 1 | UniProt (O95786) Pfam (PF00270) Pfam (PF18119) Pfam (PF00271) Pfam (PF11648) | HOMO SAPIENS (HUMAN) | DDX58, DEAD BOX PROTEIN 58, RIG-I-LIKE RECEPTOR 1, RLR-1, RETINOIC ACID-INDUCIBLE GENE 1 PROTEIN, RIG-1, RETINOIC ACID-INDUCIBLE GENE I PROTEIN, RIG-I |
| 2 | B (C) | 5'-R-PPP(GP*GP*CP*GP*CP*GP*GP*CP*UP*UP*CP*GP*GP*CP *CP*GP*CP*GP*CP*C)-3' | polymer | 20 | 6580.8 | 1 | 5' TRI-PHOSPHORYLATED RNA | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F, G (A, C) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 239 - 925 (UniProt: O95786)
| PDB | External Database | Details |
|---|---|---|
| Asn 306 | Gln 306 | conflict |
| Asp 828 | Glu 828 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85267.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 516.9 | |
| All* | Total formula weight | 85784.5 |
