3OG8

Crystal structure of human RIG-I CTD bound to a 14-bp blunt-ended dsRNA

Summary for 3OG8

• Entry DOI: 10.2210/pdb3og8/pdb
• Related: 3LRN 3LRR
• Descriptor: Antiviral innate immune response receptor RIG-I, RNA (5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION, ... (4 entities in total)
• Functional Keywords: innate immunity, viral rna sensing, rna binding domain, ips-1, cytosolic, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: O95786
• Total number of polymer chains: 4
• Total formula weight: 39239.28

Authors

Li, P. (deposition date: 2010-08-16, release date: 2010-11-03, Last modification date: 2024-02-21)

• Primary citation: Lu, C.,Ranjith-Kumar, C.T.,Hao, L.,Kao, C.C.,Li, P.; Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.; Nucleic Acids Res., 39:1565-1575, 2011; PubMed: 20961956; DOI: 10.1093/nar/gkq974

Experimental method

X-RAY DIFFRACTION (2.4 Å)