3OG8
Crystal structure of human RIG-I CTD bound to a 14-bp blunt-ended dsRNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Antiviral innate immune response receptor RIG-I | polymer | 128 | 15046.5 | 2 | UniProt (O95786) Pfam (PF11648) In PDB | Homo sapiens (human) | ATP-dependent RNA helicase DDX58,DEAD box protein 58,RIG-I-like receptor 1,RLR-1,RNA sensor RIG-I,Retinoic acid-inducible gene 1 protein,RIG-1,Retinoic acid-inducible gene I protein,RIG-I |
2 | C, D | RNA (5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3') | polymer | 14 | 4507.8 | 2 | Synthetic construct | ||
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A, B: 802 - 925 (UniProt: O95786)
PDB | External Database | Details |
---|---|---|
Met 801 | - | initiating methionine |
Ser 829 | Cys 829 | engineered mutation |
Leu 926 | - | expression tag |
Glu 927 | - | expression tag |
His 928 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 39108.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 39239.3 |