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5F9F

Crystal structure of RIG-I helicase-RD in complex with 24-mer blunt-end hairpin RNA

Summary for 5F9F
Entry DOI10.2210/pdb5f9f/pdb
Related5F98 5F9H
DescriptorProbable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ... (7 entities in total)
Functional Keywordscomplex, rig-i, capped rna, self versus non-self, innate immunity, hydrolase-rna complex, hydrolase/rna
Biological sourceHomo sapiens (Human)
More
Cellular locationCytoplasm: O95786
Total number of polymer chains12
Total formula weight525575.78
Authors
Wang, C.,Marcotrigiano, J.,Miller, M.T.,Jiang, F. (deposition date: 2015-12-09, release date: 2016-01-13, Last modification date: 2023-09-27)
Primary citationDevarkar, S.C.,Wang, C.,Miller, M.T.,Ramanathan, A.,Jiang, F.,Khan, A.G.,Patel, S.S.,Marcotrigiano, J.
Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113:596-601, 2016
Cited by
PubMed: 26733676
DOI: 10.1073/pnas.1515152113
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.601 Å)
Structure validation

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