Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 33 件
3QEK
DownloadVisualize
BU of 3qek by Molmil
Crystal structure of amino terminal domain of the NMDA receptor subunit GluN1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NMDA glutamate receptor subunit, POTASSIUM ION, ...
著者Karakas, E, Simorowski, N, Furukawa, H.
登録日2011-01-20
公開日2011-06-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
6E7R
DownloadVisualize
BU of 6e7r by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7U
DownloadVisualize
BU of 6e7u by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-31
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7T
DownloadVisualize
BU of 6e7t by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7X
DownloadVisualize
BU of 6e7x by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-97
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7V
DownloadVisualize
BU of 6e7v by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-88
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
3QEL
DownloadVisualize
BU of 3qel by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with ifenprodil
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, Glutamate [NMDA] receptor subunit epsilon-2, ...
著者Karakas, E, Simorowski, N, Furukawa, H.
登録日2011-01-20
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
6E7W
DownloadVisualize
BU of 6e7w by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-115
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
5TQ0
DownloadVisualize
BU of 5tq0 by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in the presence of EDTA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ...
著者Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
6E7S
DownloadVisualize
BU of 6e7s by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
5EWM
DownloadVisualize
BU of 5ewm by Molmil
CRYSTAL STRUCTURE OF AMINO TERMINAL DOMAINS OF THE NMDA RECEPTOR SUBUNIT GLUN1 AND GLUN2B IN COMPLEX WITH EVT-101
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[3-[bis(fluoranyl)methyl]-4-fluoranyl-phenyl]-3-[(2-methylimidazol-1-yl)methyl]pyridazine, Glutamate receptor ionotropic, ...
著者Pandit, J.
登録日2015-11-20
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.
Mol.Pharmacol., 89, 2016
5EWJ
DownloadVisualize
BU of 5ewj by Molmil
CRYSTAL STRUCTURE OF AMINO TERMINAL DOMAINS OF THE NMDA RECEPTOR SUBUNIT GLUN1 AND GLUN2B IN COMPLEX WITH IFENPRODIL
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, Glutamate receptor ionotropic, ...
著者Pandit, J.
登録日2015-11-20
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.
Mol.Pharmacol., 89, 2016
8G18
DownloadVisualize
BU of 8g18 by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-108
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ...
著者Regan, M.C, Furukawa, H.
登録日2023-02-01
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model.
Acs Chem Neurosci, 14, 2023
5B3J
DownloadVisualize
BU of 5b3j by Molmil
Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
分子名称: Fab, heavy chain, light chain, ...
著者Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H.
登録日2016-03-01
公開日2016-05-11
最終更新日2022-03-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Nature, 534, 2016
5TPW
DownloadVisualize
BU of 5tpw by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at the GluN2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ...
著者Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.909 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
5EWL
DownloadVisualize
BU of 5ewl by Molmil
CRYSTAL STRUCTURE OF AMINO TERMINAL DOMAINS OF THE NMDA RECEPTOR SUBUNIT GLUN1 AND GLUN2B IN COMPLEX WITH MK-22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 2B, ...
著者Pandit, J.
登録日2015-11-20
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.
Mol.Pharmacol., 89, 2016
3QEM
DownloadVisualize
BU of 3qem by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with Ro 25-6981
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, Glutamate [NMDA] receptor subunit epsilon-2, ...
著者Karakas, E, Simorowski, N, Furukawa, H.
登録日2011-01-20
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
5TPZ
DownloadVisualize
BU of 5tpz by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in apo closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 2B, ...
著者Romero-Hernandez, A, Simorwski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.095 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
5TQ2
DownloadVisualize
BU of 5tq2 by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at GluN1 and GluN2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ...
著者Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.289 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
4TLL
DownloadVisualize
BU of 4tll by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 1
分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
著者Gouaux, E, Lee, C.-H, Lu, W.
登録日2014-05-30
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
5UN1
DownloadVisualize
BU of 5un1 by Molmil
Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor
分子名称: (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Song, X, Gouaux, E.
登録日2017-01-30
公開日2018-02-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Mechanism of NMDA receptor channel block by MK-801 and memantine.
Nature, 556, 2018
4TLM
DownloadVisualize
BU of 4tlm by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 2
分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
著者Gouaux, E, Lee, C.-H, Lu, W.
登録日2014-05-30
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
5UOW
DownloadVisualize
BU of 5uow by Molmil
Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, MK-801 and a GluN2B-specific Fab, at pH 6.5
分子名称: (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Lu, W, Du, J, Goehring, A, Gouaux, E.
登録日2017-02-01
公開日2017-03-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.
Science, 355, 2017
7TE6
DownloadVisualize
BU of 7te6 by Molmil
Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Regan, M, Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.55 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
5UP2
DownloadVisualize
BU of 5up2 by Molmil
Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, Ro 25-6981, MK-801 and a GluN2B-specific Fab, at pH 6.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GluN2B-specific Fab, ...
著者Lu, W, Du, J, Goehring, A, Gouaux, E.
登録日2017-02-01
公開日2017-03-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.
Science, 355, 2017

 

12>

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon