5UN1

Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor

Summary for 5UN1

• Entry DOI: 10.2210/pdb5un1/pdb
• Descriptor: N-methyl-D-aspartate receptor subunit NR1-3a, Ionotropic glutamate receptor subunit NR2B, GLYCINE, ... (9 entities in total)
• Functional Keywords: complex, arrangement, channel blocker, membrane proteins-inhibitor complex, membrane proteins/inhibitor
• Biological source: Xenopus laevis (African clawed frog); More
• Cellular location: Cell membrane ; Multi- pass membrane protein : A7XY94
• Total number of polymer chains: 8
• Total formula weight: 408395.75

Authors

Song, X.,Gouaux, E. (deposition date: 2017-01-30, release date: 2018-02-07, Last modification date: 2023-10-04)

• Primary citation: Song, X.,Jensen, M.O.,Jogini, V.,Stein, R.A.,Lee, C.H.,Mchaourab, H.S.,Shaw, D.E.,Gouaux, E.; Mechanism of NMDA receptor channel block by MK-801 and memantine.; Nature, 556:515-519, 2018; PubMed: 29670280; DOI: 10.1038/s41586-018-0039-9

Experimental method

X-RAY DIFFRACTION (3.6 Å)