7TE6

Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody

Summary for 7TE6

• Entry DOI: 10.2210/pdb7te6/pdb
• Descriptor: Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2B, Fab5 heavy chain, ... (4 entities in total)
• Functional Keywords: fab fragment complexed to the receptor, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 8
• Total formula weight: 263999.79

Authors

Regan, M.,Tajima, N.,Furukawa, H. (deposition date: 2022-01-04, release date: 2022-03-02, Last modification date: 2023-10-18)

• Primary citation: Tajima, N.,Simorowski, N.,Yovanno, R.A.,Regan, M.C.,Michalski, K.,Gomez, R.,Lau, A.Y.,Furukawa, H.; Development and characterization of functional antibodies targeting NMDA receptors.; Nat Commun, 13:923-923, 2022; PubMed: 35177668; DOI: 10.1038/s41467-022-28559-3

Experimental method

X-RAY DIFFRACTION (4.55 Å)