4A4D
| Crystal structure of the N-terminal domain of the Human DEAD-BOX RNA helicase DDX5 (P68) | Descriptor: | PROBABLE ATP-DEPENDENT RNA HELICASE DDX5 | Authors: | Dutta, S, Choi, Y.W, Kotaka, M, Fielding, B.C, Tan, Y.J. | Deposit date: | 2011-10-11 | Release date: | 2012-08-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Variable N-Terminal Region of Ddx5 Contains Structural Elements and Auto-Inhibits its Interaction with Ns5B of Hepatitis C Virus. Biochem.J., 446, 2012
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8KCA
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3FE2
| Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX5, ... | Authors: | Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-11-27 | Release date: | 2008-12-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases Plos One, 5, 2010
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3DKP
| Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Lehtio, L, Karlberg, T, Andersson, J, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, van den Berg, S, Welin, M, Wisniewska, M, Wikstrom, M, Schueler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-06-25 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases. Plos One, 5, 2010
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3IUY
| Crystal structure of DDX53 DEAD-box domain | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX53 | Authors: | Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-31 | Release date: | 2009-10-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases. Plos One, 5, 2010
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5E3H
| Structural Basis for RNA Recognition and Activation of RIG-I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... | Authors: | Jiang, F, Miller, M.T, Marcotrigiano, J. | Deposit date: | 2015-10-02 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature, 479, 2011
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2E29
| Solution structure of the GUCT domain from human ATP-dependent RNA helicase DDX50, DEAD box protein 50 | Descriptor: | ATP-dependent RNA helicase DDX50 | Authors: | Ohnishi, S, Paakkonen, K, Guntert, P, Sato, M, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-11-10 | Release date: | 2007-05-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the GUCT domain from human RNA helicase II/Gubeta reveals the RRM fold, but implausible RNA interactions Proteins, 74, 2008
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8V84
| 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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8V85
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8V87
| 60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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8V83
| 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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6KYV
| Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs | Descriptor: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3'), ZINC ION | Authors: | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | Deposit date: | 2019-09-20 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs. Rna Biol., 17, 2020
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2RMJ
| Solution structure of RIG-I C-terminal domain | Descriptor: | Probable ATP-dependent RNA helicase DDX58 | Authors: | Takahasi, K, Yoneyama, M, Nihishori, T, Hirai, R, Narita, R, Gale Jr, M, Fujita, T, Inagaki, F. | Deposit date: | 2007-10-23 | Release date: | 2008-03-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses Mol.Cell, 29, 2008
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4NQK
| Structure of an Ubiquitin complex | Descriptor: | Probable ATP-dependent RNA helicase DDX58, Ubiquitin | Authors: | Peisley, A, Wu, B, Hur, S. | Deposit date: | 2013-11-25 | Release date: | 2014-03-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I. Nature, 509, 2014
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4BPB
| STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I | Descriptor: | 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ... | Authors: | Luo, D, Pyle, A.M. | Deposit date: | 2013-05-23 | Release date: | 2013-06-19 | Method: | X-RAY DIFFRACTION (2.584 Å) | Cite: | Structural Insights Into RNA Recognition by Rig-I. Cell(Cambridge,Mass.), 147, 2011
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6GPG
| Structure of the RIG-I Singleton-Merten syndrome variant C268F | Descriptor: | MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), ... | Authors: | Laessig, C, Lammens, K, Hopfner, K.-P. | Deposit date: | 2018-06-05 | Release date: | 2018-08-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants. Elife, 7, 2018
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4P4H
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4ON9
| DECH box helicase domain | Descriptor: | CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58, SULFATE ION | Authors: | Deimling, T, Witte, G, Hopfner, K.P. | Deposit date: | 2014-01-28 | Release date: | 2014-07-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal and solution structure of the human RIG-I SF2 domain Acta Crystallogr.,Sect.F, 70, 2014
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2YKG
| Structural insights into RNA recognition by RIG-I | Descriptor: | 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ... | Authors: | Luo, D, Pyle, A.M. | Deposit date: | 2011-05-27 | Release date: | 2011-10-26 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Insights Into RNA Recognition by Rig-I. Cell(Cambridge,Mass.), 147, 2011
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2LWE
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2LWD
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2YQP
| Solution structure of the zf-HIT domain in DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 | Descriptor: | Probable ATP-dependent RNA helicase DDX59, ZINC ION | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the zf-HIT domain in DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 To be Published
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5F9F
| Crystal structure of RIG-I helicase-RD in complex with 24-mer blunt-end hairpin RNA | Descriptor: | (R,R)-2,3-BUTANEDIOL, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ... | Authors: | Wang, C, Marcotrigiano, J, Miller, M.T, Jiang, F. | Deposit date: | 2015-12-09 | Release date: | 2016-01-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc.Natl.Acad.Sci.USA, 113, 2016
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5F98
| Crystal structure of RIG-I in complex with Cap-0 RNA | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ... | Authors: | Wang, C, Marcotrigiano, J, Miller, M, Jiang, F. | Deposit date: | 2015-12-09 | Release date: | 2016-01-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.28 Å) | Cite: | Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc.Natl.Acad.Sci.USA, 113, 2016
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6BZH
| Structure of mouse RIG-I tandem CARDs | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58 | Authors: | Kershaw, N.J, D'Cruz, A.A, Babon, J.J, Nicholson, S.E. | Deposit date: | 2017-12-24 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Identification of a second binding site on the TRIM25 B30.2 domain. Biochem. J., 475, 2018
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