4P4H
Caught-in-action signaling complex of RIG-I 2CARD domain and MAVS CARD domain
Summary for 4P4H
Entry DOI | 10.2210/pdb4p4h/pdb |
Descriptor | Probable ATP-dependent RNA helicase DDX58, Mitochondrial antiviral-signaling protein, Ubiquitin-60S ribosomal protein L40 (3 entities in total) |
Functional Keywords | signaling protein, signaling complex |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: O95786 Mitochondrion outer membrane: Q7Z434 Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm : P62987 |
Total number of polymer chains | 21 |
Total formula weight | 334392.81 |
Authors | |
Primary citation | Wu, B.,Peisley, A.,Tetrault, D.,Li, Z.,Egelman, E.H.,Magor, K.E.,Walz, T.,Penczek, P.A.,Hur, S. Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I. Mol.Cell, 55:511-523, 2014 Cited by PubMed: 25018021DOI: 10.1016/j.molcel.2014.06.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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