3FE2
Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP
Summary for 3FE2
Entry DOI | 10.2210/pdb3fe2/pdb |
Descriptor | Probable ATP-dependent RNA helicase DDX5, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | rna helicase, dead, adp, atp-binding, hydrolase, nucleotide-binding, rna-binding, helicase, methylation, mrna processing, mrna splicing, nucleus, phosphoprotein, spliceosome, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus, nucleolus: P17844 |
Total number of polymer chains | 2 |
Total formula weight | 55720.88 |
Authors | Karlberg, T.,Siponen, M.I.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Lehtio, L.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wikstrom, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2008-11-27, release date: 2008-12-16, Last modification date: 2023-11-01) |
Primary citation | Schutz, P.,Karlberg, T.,van den Berg, S.,Collins, R.,Lehtio, L.,Hogbom, M.,Holmberg-Schiavone, L.,Tempel, W.,Park, H.W.,Hammarstrom, M.,Moche, M.,Thorsell, A.G.,Schuler, H. Comparative Structural Analysis of Human DEAD-Box RNA Helicases Plos One, 5:e12791-e12791, 2010 Cited by PubMed: 20941364DOI: 10.1371/journal.pone.0012791 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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