7L9P
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![BU of 7l9p by Molmil](/molmil-images/mine/7l9p) | Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pachytene checkpoint protein 2 homolog, ... | Authors: | Xie, W, Patel, D.J. | Deposit date: | 2021-01-04 | Release date: | 2021-03-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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6XRR
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![BU of 6xrr by Molmil](/molmil-images/mine/6xrr) | Structure of SciW bound to the Rhs1 Transmembrane Domain from Salmonella typhimurium | Descriptor: | Putative cytoplasmic protein, RHS repeat protein, SULFATE ION | Authors: | Sachar, K, Ahmad, S, Whitney, J.C, Prehna, G. | Deposit date: | 2020-07-13 | Release date: | 2020-12-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones. Elife, 9, 2020
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6D8Z
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6XWS
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![BU of 6xws by Molmil](/molmil-images/mine/6xws) | Crystal Structure of Drosophila CAL1 1-160 bound to CENP-A/H4 | Descriptor: | Chromosome alignment defect 1,Chromosome alignment defect 1, Histone H3-like centromeric protein cid, Histone H4 | Authors: | Jeyaprakash, A.A, Medina-Pritchard, B, Lazou, V, Zou, J, Byron, O, Abad, M.A, Rappsilber, J, Heun, P. | Deposit date: | 2020-01-24 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (4.36 Å) | Cite: | Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. Embo J., 39, 2020
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6KNK
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![BU of 6knk by Molmil](/molmil-images/mine/6knk) | Crystal structure of SbnH in complex with citryl-diaminoethane | Descriptor: | (2S)-2-{2-[(2-AMINOETHYL)AMINO]-2-OXOETHYL}-2-HYDROXYBUTANEDIOIC ACID, (2~{S})-2-[2-[2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]ethylamino]-2-oxidanylidene-ethyl]-2-oxidanyl-butanedioic acid, PHOSPHATE ION, ... | Authors: | Tang, J, Ju, Y, Zhou, H. | Deposit date: | 2019-08-05 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insights into Substrate Recognition and Activity Regulation of the Key Decarboxylase SbnH in Staphyloferrin B Biosynthesis. J.Mol.Biol., 431, 2019
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6DAT
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![BU of 6dat by Molmil](/molmil-images/mine/6dat) | ETS1 in complex with synthetic SRR mimic | Descriptor: | Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide | Authors: | Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P. | Deposit date: | 2018-05-02 | Release date: | 2019-01-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35002637 Å) | Cite: | The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J. Mol. Biol., 431, 2019
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6JTG
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6JY3
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![BU of 6jy3 by Molmil](/molmil-images/mine/6jy3) | Monomeric Form of Bovine Heart Cytochrome c Oxidase in the Fully Oxidized State | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (2S,3S,4S,5S,6R)-2-(2-decoxyethoxy)-6-(hydroxymethyl)oxane-3,4,5-triol, ... | Authors: | Shinzawa-Itoh, K, Muramoto, K. | Deposit date: | 2019-04-26 | Release date: | 2019-09-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Monomeric structure of an active form of bovine cytochromecoxidase. Proc.Natl.Acad.Sci.USA, 116, 2019
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7M05
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5KVH
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![BU of 5kvh by Molmil](/molmil-images/mine/5kvh) | Crystal structure of human apoptosis-inducing factor with W196A mutation | Descriptor: | Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Brosey, C.A, Nix, J, Ellenberger, T, Tainer, J.A. | Deposit date: | 2016-07-14 | Release date: | 2016-11-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.273 Å) | Cite: | Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor. Structure, 24, 2016
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2GIT
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1HQF
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![BU of 1hqf by Molmil](/molmil-images/mine/1hqf) | CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH N-HYDROXY-L-ARGININE | Descriptor: | ARGINASE 1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE | Authors: | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2000-12-16 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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5OBZ
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![BU of 5obz by Molmil](/molmil-images/mine/5obz) | low resolution structure of the p34ct/p44ct minimal complex | Descriptor: | Putative transcription factor, ZINC ION | Authors: | Schoenwetter, E, Koelmel, W, Schmitt, D.R, Kuper, J, Kisker, C. | Deposit date: | 2017-06-29 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH. Nucleic Acids Res., 45, 2017
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6C6L
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![BU of 6c6l by Molmil](/molmil-images/mine/6c6l) | Yeast Vacuolar ATPase Vo in lipid nanodisc | Descriptor: | V-type proton ATPase subunit a, vacuolar isoform, V-type proton ATPase subunit c, ... | Authors: | Roh, S, Stam, N.J, Hryc, C, Couoh-Cardel, S, Pintilie, G, Chiu, W, Wilkens, S. | Deposit date: | 2018-01-19 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The 3.5- angstrom CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase VoProton Channel. Mol. Cell, 69, 2018
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7BZW
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![BU of 7bzw by Molmil](/molmil-images/mine/7bzw) | Structure of Hsp21 | Descriptor: | Heat shock protein 21, chloroplastic | Authors: | Lau, W.C.Y. | Deposit date: | 2020-04-28 | Release date: | 2021-04-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of substrate recognition and thermal protection by a small heat shock protein. Nat Commun, 12, 2021
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1HQG
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![BU of 1hqg by Molmil](/molmil-images/mine/1hqg) | CRYSTAL STRUCTURE OF THE H141C ARGINASE VARIANT COMPLEXED WITH PRODUCTS ORNITHINE AND UREA | Descriptor: | ARGINASE 1, L-ornithine, MANGANESE (II) ION, ... | Authors: | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2000-12-16 | Release date: | 2001-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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6KIU
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![BU of 6kiu by Molmil](/molmil-images/mine/6kiu) | Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) | Descriptor: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | Authors: | Huang, J, Xue, H, Yao, T. | Deposit date: | 2019-07-20 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
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6KJB
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![BU of 6kjb by Molmil](/molmil-images/mine/6kjb) | wild-type apo-form E. coli ATCase holoenzyme with an unusual open conformation of R167 | Descriptor: | Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION | Authors: | Wang, N, Lei, Z, Zheng, J, Jia, Z.C. | Deposit date: | 2019-07-22 | Release date: | 2020-06-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Conformational Plasticity of the Active Site Entrance inE. coliAspartate Transcarbamoylase and Its Implication in Feedback Regulation. Int J Mol Sci, 21, 2020
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5KVI
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![BU of 5kvi by Molmil](/molmil-images/mine/5kvi) | Crystal structure of monomeric human apoptosis-inducing factor with E413A/R422A/R430A mutations | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Apoptosis-inducing factor 1, mitochondrial, ... | Authors: | Brosey, C.A, Nix, J, Ellenberger, T, Tainer, J.A. | Deposit date: | 2016-07-14 | Release date: | 2016-11-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.995 Å) | Cite: | Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor. Structure, 24, 2016
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6HLU
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2H3X
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![BU of 2h3x by Molmil](/molmil-images/mine/2h3x) | Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes Faecalis (Form 3) | Descriptor: | Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION | Authors: | Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S. | Deposit date: | 2006-05-23 | Release date: | 2006-11-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis. Biochemistry, 45, 2006
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5L0I
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6U8P
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![BU of 6u8p by Molmil](/molmil-images/mine/6u8p) | Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA | Descriptor: | CpGpA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Gao, L, Song, J. | Deposit date: | 2019-09-05 | Release date: | 2020-06-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
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6HMT
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![BU of 6hmt by Molmil](/molmil-images/mine/6hmt) | Ternary complex of Estrogen Receptor alpha peptide and 14-3-3 sigma C42 mutant bound to disulfide fragment PPI stabilizer 2 | Descriptor: | 14-3-3 protein sigma, 2-(4-chloranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen Receptor, ... | Authors: | Sijbesma, E, Hallenbeck, K.K, Leysen, S, Arkin, M.R, Ottmann, C. | Deposit date: | 2018-09-12 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers. J. Am. Chem. Soc., 141, 2019
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7MON
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![BU of 7mon by Molmil](/molmil-images/mine/7mon) | Structure of human RIPK3-MLKL complex | Descriptor: | Mixed lineage kinase domain-like protein, N-[4-({2-[(cyclopropanecarbonyl)amino]pyridin-4-yl}oxy)-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 3 | Authors: | Meng, Y, Davies, K.A, Czabotar, P.E, Murphy, J.M. | Deposit date: | 2021-05-03 | Release date: | 2021-11-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nat Commun, 12, 2021
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