5KVI

Crystal structure of monomeric human apoptosis-inducing factor with E413A/R422A/R430A mutations

Summary for 5KVI

Entry DOI	10.2210/pdb5kvi/pdb
Descriptor	Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	oxidoreductase, flavoprotein, mitochondria cell death
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	60356.25
Authors	Brosey, C.A.,Nix, J.,Ellenberger, T.,Tainer, J.A. (deposition date: 2016-07-14, release date: 2016-11-16, Last modification date: 2023-10-04)
Primary citation	Brosey, C.A.,Ho, C.,Long, W.Z.,Singh, S.,Burnett, K.,Hura, G.L.,Nix, J.C.,Bowman, G.R.,Ellenberger, T.,Tainer, J.A. Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor. Structure, 24:2067-2079, 2016 Cited by PubMed: 27818101 DOI: 10.1016/j.str.2016.09.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.995 Å)

Structure validation