1HQF

CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH N-HYDROXY-L-ARGININE

Summary for 1HQF

• Entry DOI: 10.2210/pdb1hqf/pdb
• Related: 1rla
• Descriptor: ARGINASE 1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE, ... (4 entities in total)
• Functional Keywords: arginase, n-hydroxy-l-arginine (noha), binuclear manganese cluster, metalloenzyme, hydrolase
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Cytoplasm: P07824
• Total number of polymer chains: 3
• Total formula weight: 105957.52

Authors

Cox, J.D.,Cama, E.,Colleluori, D.M.,Ash, D.E.,Christianson, D.W. (deposition date: 2000-12-16, release date: 2001-04-04, Last modification date: 2024-02-07)

• Primary citation: Cox, J.D.,Cama, E.,Colleluori, D.M.,Pethe, S.,Boucher, J.L.,Mansuy, D.,Ash, D.E.,Christianson, D.W.; Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.; Biochemistry, 40:2689-2701, 2001; PubMed: 11258880; DOI: 10.1021/bi002318+

Experimental method

X-RAY DIFFRACTION (2.9 Å)