PDB: 46200 resultsInfo pagesStatus searchChemie searchBIRD

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6QZW	DPP8 bound to a dipeptide (MP) from the N-terminus of BRCA2 Descriptor: Dipeptidyl peptidase 8, MET-PRO, SODIUM ION Authors: Ross, B, Geiss-Friedlander, R, Huber, R. Deposit date: 2019-03-12 Release date: 2020-09-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair Biorxiv, 2020
5BYG	X-ray structure of AAV2 OBD-AAVS1 complex 2:1 Descriptor: CITRIC ACID, DNA (5'-D(*CP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*GP*CP*CP*GP*A)-3'), ... Authors: Musayev, F.N, Escalante, C.R. Deposit date: 2015-06-10 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1. J.Biol.Chem., 290, 2015
2LMC	Structure of T7 transcription factor Gp2-E. coli RNAp jaw domain complex Descriptor: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit beta Authors: Liu, M. Deposit date: 2011-11-29 Release date: 2012-03-14 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural and Mechanistic Basis for the Inhibition of Escherichia coli RNA Polymerase by T7 Gp2. Mol.Cell, 47, 2012
2FIH	Crystal Structure Analysis of the B-DNA Dodecamer CGCGAA-aU-TCGCG, with Incorporated Arabino-Uridine (aU) Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*(UAR)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION Authors: Egli, M, Li, F. Deposit date: 2005-12-29 Release date: 2006-05-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.13 Å) Cite: 2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. Biochemistry, 45, 2006
2FII	Crystal Structure Analysis of the B-DNA Dodecamer CGCGAAT-aU-CGCG, with Incorporated Arabino-Uridin (aU) Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(UAR)P*CP*GP*CP*G)-3', MAGNESIUM ION Authors: Egli, M, Li, F. Deposit date: 2005-12-29 Release date: 2006-05-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.24 Å) Cite: 2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. Biochemistry, 45, 2006
2FIJ	Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-aU-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and Arabino-Uridine (aU) Descriptor: 5'-D(*GP*CP*GP*TP*(A2M)P*(UAR)P*AP*CP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III) Authors: Egli, M, Li, F. Deposit date: 2005-12-29 Release date: 2006-05-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.19 Å) Cite: 2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. Biochemistry, 45, 2006
2G8K	B. halodurans RNase H catalytic domain D192N mutant in complex with Ca2+ and RNA/DNA hybrid (non-P nick at the active site) Descriptor: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', CALCIUM ION, ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-02 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
2G8H	B. halodurans RNase H catalytic domain D192N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site) Descriptor: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', MAGNESIUM ION, ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-02 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
5BS3	Crystal Structure of S.A. gyrase in complex with Compound 7 Descriptor: (4R)-3-fluoro-4-hydroxy-4-{[(1r,4R)-4-{[(3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-yl)methyl]amino}-2-oxabicyclo[2.2.2]oct-1-yl]methyl}-4,5-dihydro-7H-pyrrolo[3,2,1-de][1,5]naphthyridin-7-one, DNA gyrase subunit A and B, DNA/RNA (5'-R(P*AP*GP*CP*CP*G)-D(P*T)-R(P*AP*GP*GP*GP*CP*CP*C)-D(P*T)-R(P*AP*CP*GP*GP*C)-D(P*T)-3'), ... Authors: Lu, J, Patel, S, Soisson, S. Deposit date: 2015-06-01 Release date: 2015-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2). Bioorg.Med.Chem.Lett., 25, 2015
1R7M	The homing endonuclease I-SceI bound to its DNA recognition region Descriptor: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*TP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ... Authors: Moure, C.M, Gimble, F.S, Quiocho, F.A. Deposit date: 2003-10-21 Release date: 2004-10-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.25 Å) Cite: The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity J.Mol.Biol., 334, 2003
2N4P	Solution structure of the n-terminal domain of tdp-43 Descriptor: TAR DNA-binding protein 43 Authors: Mompean, M, Romano, V, Pantoja-Uceda, D, Stuani, C, Baralle, F, Buratti, E, Laurents, D.V. Deposit date: 2015-06-26 Release date: 2016-01-20 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The TDP-43 N-terminal domain structure at high resolution. Febs J., 283, 2016
2N4H	Solution Structure of the Q343R Mutant of TDP-43 Amyloidogenic Core Region Descriptor: TAR DNA-binding protein 43 Authors: Jiang, L, Zhao, J, Hu, H. Deposit date: 2015-06-18 Release date: 2016-04-20 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation Sci Rep, 6, 2016
4BHB	Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE Descriptor: GLYCEROL, METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE Authors: Miggiano, R, Casazza, V, Garavaglia, S, Ciaramella, M, Perugino, G, Rizzii, M, Rossi, F. Deposit date: 2013-04-02 Release date: 2013-04-17 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Biochemical and Structural Studies of the Mycobacterium Tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants. J.Bacteriol., 195, 2013
6JRF	Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium Descriptor: CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ... Authors: Lin, Z, Lin, H, Zhang, D, Yuan, C. Deposit date: 2019-04-03 Release date: 2019-10-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.047 Å) Cite: Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
5CR2	E. coli MazF in complex with single strand DNA substrate analog Descriptor: Endoribonuclease MazF, ssDNA substrate analog Authors: Zorzini, V, Loris, R. Deposit date: 2015-07-22 Release date: 2016-04-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF. J.Biol.Chem., 291, 2016
1JNB	CONNECTOR PROTEIN FROM BACTERIOPHAGE PHI29 Descriptor: UPPER COLLAR PROTEIN Authors: Simpson, A.A, Leiman, P.G, Tao, Y, He, Y, Badasso, M.O, Jardine, P.J, Anderson, D.L, Rossmann, M.G. Deposit date: 2001-07-23 Release date: 2001-08-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structure determination of the head-tail connector of bacteriophage phi29. Acta Crystallogr.,Sect.D, 57, 2001
1Y8L	Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(trifluoro)ethyl] Thymidine (T*) Descriptor: 5'-D(*GP*CP*GP*TP*AP*(TFE)P*AP*CP*GP*C)-3'), MAGNESIUM ION, SPERMINE Authors: Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. Deposit date: 2004-12-13 Release date: 2005-06-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications. Biochemistry, 44, 2005
1Y8V	Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-propyl Thymidine (T*) Descriptor: 5'-D(*GP*CP*GP*TP*AP*(P2T)P*AP*CP*GP*C)-3' Authors: Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. Deposit date: 2004-12-13 Release date: 2005-06-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications. Biochemistry, 44, 2005
2G8I	B. halodurans RNase H catalytic domain D192N mutant in complex with Mn2+ and RNA/DNA hybrid (non-P nick at the active site) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-02 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
2G8W	B. halodurans RNase H catalytic domain E188A mutant in complex with Ca2+ and RNA/DNA hybrid Descriptor: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(P*UP*CP*GP*AP*CP*A)-3', CALCIUM ION, ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-03 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
1Y9F	Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-allyl Thymidine (T*) Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2AT)P*AP*CP*GP*C)-3') Authors: Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. Deposit date: 2004-12-15 Release date: 2005-06-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications. Biochemistry, 44, 2005
2G8V	B. halodurans RNase H catalytic domain E188A mutant in complex with Mg2+ and RNA/DNA hybrid (reaction product) Descriptor: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(P*UP*CP*GP*AP*CP*A)-3', ETHANOL, ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-03 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
7OAR	Crystal structure of helicase Pif1 from Thermus oshimai in complex with parallel G-quadruplex Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (28-MER), MAGNESIUM ION, ... Authors: Dai, Y.X, Liu, N.N, Guo, H.L, Chen, W.F, Rety, S, Xi, X.G. Deposit date: 2021-04-20 Release date: 2022-03-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Structural mechanism underpinning Thermus oshimai Pif1-mediated G-quadruplex unfolding. Embo Rep., 23, 2022
2G8F	B. halodurans RNase H catalytic domain E188A mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site) Descriptor: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', CHLORIDE ION, ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-02 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
2G8U	B. halodurans RNase H catalytic domain D132N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site) Descriptor: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', MAGNESIUM ION, ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-03 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006

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