6QZW

DPP8 bound to a dipeptide (MP) from the N-terminus of BRCA2

Summary for 6QZW

• Entry DOI: 10.2210/pdb6qzw/pdb
• Descriptor: Dipeptidyl peptidase 8, MET-PRO, SODIUM ION, ... (4 entities in total)
• Functional Keywords: dpp8, dpp9, brca2, dipeptide, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 311212.02

Authors

Ross, B.,Geiss-Friedlander, R.,Huber, R. (deposition date: 2019-03-12, release date: 2020-09-30, Last modification date: 2024-01-24)

• Primary citation: Silva-Garcia, M.,Bolgi, O.,Ross, B.,Pilla, E.,Kari, V.,Killisch, M.,Stark, N.,Lenz, C.,Spitzner, M.,Gorrell, M.D.,Grade, M.,Urlaub, H.,Dobbelstein, M.,Huber, R.,Geiss-Friedlander, R.; Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair; Biorxiv, 2020; DOI: 10.1101/2020.08.24.265033

Experimental method

X-RAY DIFFRACTION (3.2 Å)