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6QZW

DPP8 bound to a dipeptide (MP) from the N-terminus of BRCA2

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006508biological_processproteolysis
A0006955biological_processimmune response
A0008236molecular_functionserine-type peptidase activity
A0008239molecular_functiondipeptidyl-peptidase activity
A0043069biological_processnegative regulation of programmed cell death
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006508biological_processproteolysis
B0006955biological_processimmune response
B0008236molecular_functionserine-type peptidase activity
B0008239molecular_functiondipeptidyl-peptidase activity
B0043069biological_processnegative regulation of programmed cell death
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006508biological_processproteolysis
C0006955biological_processimmune response
C0008236molecular_functionserine-type peptidase activity
C0008239molecular_functiondipeptidyl-peptidase activity
C0043069biological_processnegative regulation of programmed cell death
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue NA C 901
ChainResidue
CARG158
CGLN274
CGLU275
CASP278
CTYR280

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsActive site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"12534281","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29382749","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

254917

PDB entries from 2026-06-10

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