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2FIJ

Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-aU-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and Arabino-Uridine (aU)

Summary for 2FIJ
Entry DOI10.2210/pdb2fij/pdb
Related2FIH 2FII 2FIL
Descriptor5'-D(*GP*CP*GP*TP*(A2M)P*(UAR)P*AP*CP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ... (4 entities in total)
Functional Keywordsarabinonucleic acid, sugar modifications, a-form dna, dna
Total number of polymer chains2
Total formula weight6672.81
Authors
Egli, M.,Li, F. (deposition date: 2005-12-29, release date: 2006-05-23, Last modification date: 2023-08-30)
Primary citationLi, F.,Sarkhel, S.,Wilds, C.J.,Wawrzak, Z.,Prakash, T.P.,Manoharan, M.,Egli, M.
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45:4141-4152, 2006
Cited by
PubMed: 16566588
DOI: 10.1021/bi052322r
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.19 Å)
Structure validation

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