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2FIH

Crystal Structure Analysis of the B-DNA Dodecamer CGCGAA-aU-TCGCG, with Incorporated Arabino-Uridine (aU)

Summary for 2FIH
Entry DOI10.2210/pdb2fih/pdb
Related2FII 2FIJ 2FIL
Descriptor5'-D(*CP*GP*CP*GP*AP*AP*(UAR)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION (3 entities in total)
Functional Keywordsarabinonucleic acid, sugar modifications, b-form dna, dna
Total number of polymer chains2
Total formula weight7355.03
Authors
Egli, M.,Li, F. (deposition date: 2005-12-29, release date: 2006-05-23, Last modification date: 2023-08-30)
Primary citationLi, F.,Sarkhel, S.,Wilds, C.J.,Wawrzak, Z.,Prakash, T.P.,Manoharan, M.,Egli, M.
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45:4141-4152, 2006
Cited by
PubMed: 16566588
DOI: 10.1021/bi052322r
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.13 Å)
Structure validation

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