2FII

Crystal Structure Analysis of the B-DNA Dodecamer CGCGAAT-aU-CGCG, with Incorporated Arabino-Uridin (aU)

Summary for 2FII

• Entry DOI: 10.2210/pdb2fii/pdb
• Related: 2FIH 2FIJ 2FIL
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(UAR)P*CP*GP*CP*G)-3', MAGNESIUM ION (3 entities in total)
• Functional Keywords: arabinonucleic acid, sugar modifications, b-form dna, dna
• Total number of polymer chains: 2
• Total formula weight: 7355.03

Authors

Egli, M.,Li, F. (deposition date: 2005-12-29, release date: 2006-05-23, Last modification date: 2023-08-30)

• Primary citation: Li, F.,Sarkhel, S.,Wilds, C.J.,Wawrzak, Z.,Prakash, T.P.,Manoharan, M.,Egli, M.; 2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.; Biochemistry, 45:4141-4152, 2006; PubMed: 16566588; DOI: 10.1021/bi052322r

Experimental method

X-RAY DIFFRACTION (1.24 Å)