7UO2
 
 | | E.coli RNaseP Holoenzyme with Mg2+ | | Descriptor: | MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component | | Authors: | Huang, W, Taylor, D.J. | | Deposit date: | 2022-04-12 | | Release date: | 2022-09-28 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
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7UO5
 | | E.coli RNaseP Holoenzyme with Mg2+ | | Descriptor: | CALCIUM ION, RNase P RNA, Ribonuclease P protein component | | Authors: | Huang, W, Taylor, D.J. | | Deposit date: | 2022-04-12 | | Release date: | 2022-09-28 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
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8OPS
 | | Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 1 | | Descriptor: | Protein lin-28 homolog A, RNA (71-MER) Let7g, Terminal uridylyltransferase 7, ... | | Authors: | Yi, G, Ye, M, Gilbert, R.J. | | Deposit date: | 2023-04-08 | | Release date: | 2024-07-24 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.82 Å) | | Cite: | Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs.
Nat.Struct.Mol.Biol., 31, 2024
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8OPT
 | | Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 2 | | Descriptor: | Protein lin-28 homolog A, RNA (53-MER), Terminal uridylyltransferase 7, ... | | Authors: | Yi, G, Ye, M, Gilbert, R.J. | | Deposit date: | 2023-04-08 | | Release date: | 2024-07-24 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs.
Nat.Struct.Mol.Biol., 31, 2024
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7U2A
 | | Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA (GCU) | | Descriptor: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (38-MER), Serine--tRNA ligase, ... | | Authors: | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | | Deposit date: | 2022-02-23 | | Release date: | 2022-09-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
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7U2B
 | | Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(GCU-TL) | | Descriptor: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (53-MER), Serine--tRNA ligase, ... | | Authors: | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | | Deposit date: | 2022-02-23 | | Release date: | 2022-09-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
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1MJI
 | | DETAILED ANALYSIS OF RNA-PROTEIN INTERACTIONS WITHIN THE BACTERIAL RIBOSOMAL PROTEIN L5/5S RRNA COMPLEX | | Descriptor: | 50S ribosomal protein L5, 5S rRNA fragment, MAGNESIUM ION, ... | | Authors: | Perederina, A, Nevskaya, N, Nikonov, O, Nikulin, A, Dumas, P, Yao, M, Tanaka, I, Garber, M, Gongadze, G, Nikonov, S. | | Deposit date: | 2002-08-28 | | Release date: | 2003-01-21 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Detailed analysis of RNA-protein interactions within the bacterial ribosomal
protein L5/5S rRNA complex
RNA, 8, 2002
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7ZGP
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7ZGR
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1LS2
 | | Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome | | Descriptor: | Elongation Factor Tu, Phenylalanine transfer RNA | | Authors: | Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J. | | Deposit date: | 2002-05-16 | | Release date: | 2002-06-26 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (16.799999 Å) | | Cite: | Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
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6P5R
 | | Structure of T. brucei MERS1-GDP complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Mitochondrial edited mRNA stability factor 1 | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-05-30 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei.
Rna, 26, 2020
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2B63
 | | Complete RNA Polymerase II-RNA inhibitor complex | | Descriptor: | 31-MER, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... | | Authors: | Kettenberger, H, Eisenfuehr, A, Brueckner, F, Theis, M, Famulok, M, Cramer, P. | | Deposit date: | 2005-09-30 | | Release date: | 2005-12-06 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
Nat.Struct.Mol.Biol., 13, 2006
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6NL1
 | | Structure of T. brucei MERS1 protein in its apo form | | Descriptor: | Mitochondrial edited mRNA stability factor 1, SULFATE ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-01-07 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.297 Å) | | Cite: | Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei.
Rna, 26, 2020
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5ZAK
 | | Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | | Descriptor: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | | Authors: | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | | Deposit date: | 2018-02-07 | | Release date: | 2018-05-09 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
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8KDA
 | | Cryo-EM structure of Hydrogenobacter thermophilus minimal protein-only RNase P (HARP) in complex with pre-tRNAs | | Descriptor: | Aquifex aeolicus pre-tRNAVal, MAGNESIUM ION, RNA-free ribonuclease P | | Authors: | Teramoto, T, Adachi, N, Yokogawa, T, Koyasu, T, Mayanagi, K, Nakamura, T, Senda, T, Kakuta, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Cryo-EM structure of Hydrogenobacter thermophilus minimal protein-only RNase P (HARP) in complex with pre-tRNAs
To Be Published
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3WQY
 | | Crystal structure of Archaeoglobus fulgidus alanyl-tRNA synthetase in complex with wild-type tRNA(Ala) having G3.U70 | | Descriptor: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanine--tRNA ligase, MAGNESIUM ION, ... | | Authors: | Naganuma, M, Sekine, S, Yokoyama, S. | | Deposit date: | 2014-02-05 | | Release date: | 2014-06-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The selective tRNA aminoacylation mechanism based on a single G.U pair
Nature, 510, 2014
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8R8R
 | | Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*A)-3'), ... | | Authors: | Todesca, S, Sandmeir, F, Keidel, A, Conti, E. | | Deposit date: | 2023-11-29 | | Release date: | 2024-04-10 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Molecular basis of human poly(A) polymerase recruitment by mPSF.
Rna, 30, 2024
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3WQZ
 | | Crystal structure of Archaeoglobus fulgidus alanyl-tRNA synthetase in complex with a tRNA(Ala) variant having A3.U70 | | Descriptor: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanine--tRNA ligase, RNA (75-MER), ... | | Authors: | Naganuma, M, Sekine, S, Yokoyama, S. | | Deposit date: | 2014-02-05 | | Release date: | 2014-06-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.489 Å) | | Cite: | The selective tRNA aminoacylation mechanism based on a single G.U pair
Nature, 510, 2014
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6QWS
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3J0K
 | | Orientation of RNA polymerase II within the human VP16-Mediator-pol II-TFIIF assembly | | Descriptor: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | | Authors: | Bernecky, C, Grob, P, Ebmeier, C.C, Nogales, E, Taatjes, D.J. | | Deposit date: | 2011-10-04 | | Release date: | 2011-10-19 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (36 Å) | | Cite: | Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly.
Plos Biol., 9, 2011
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4XJN
 | | Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity | | Descriptor: | LEAD (II) ION, Nucleocapsid, RNA (78-MER) | | Authors: | Alayyoubi, M, Leser, G.P, Kors, C.A, Lamb, R.A. | | Deposit date: | 2015-01-08 | | Release date: | 2015-03-18 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (3.11 Å) | | Cite: | Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6LPF
 | | The crystal structure of human cytoplasmic LRS | | Descriptor: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, ... | | Authors: | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | | Deposit date: | 2020-01-10 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
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6LR6
 | | The crystal structure of human cytoplasmic LRS | | Descriptor: | 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | | Authors: | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | | Deposit date: | 2020-01-15 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.009 Å) | | Cite: | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
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5AH5
 | | Crystal structure of the ternary complex of Agrobacterium radiobacter K84 agnB2 LeuRS-tRNA-LeuAMS | | Descriptor: | 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE--TRNA LIGASE, MANGANESE (II) ION, ... | | Authors: | Palencia, A, Chopra, S, Virus, C, Schulwitz, S, Temple, B.R, Cusack, S, Reader, J.S. | | Deposit date: | 2015-02-05 | | Release date: | 2016-02-17 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Characterization of Antibiotic Self-Immunity tRNA Synthetase in Plant Tumour Biocontrol Agent.
Nat.Commun., 7, 2016
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8KD9
 | | Cryo-EM structure of Aquifex aeolicus minimal protein-only RNase P (HARP) in complex with pre-tRNAs | | Descriptor: | Aquifex aeolicus pre-tRNAVal, RNA-free ribonuclease P | | Authors: | Teramoto, T, Koyasu, T, Mayanagi, K, Yokogawa, T, Adachi, N, Nakamura, T, Senda, T, Kakuta, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Cryo-EM structure of Aquifex aeolicus minimal protein-only RNase P (HARP) in complex with pre-tRNAs
To Be Published
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