7U2A

Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA (GCU)

Summary for 7U2A

• Entry DOI: 10.2210/pdb7u2a/pdb
• EMDB information: 26310
• Descriptor: RNA (38-MER), Serine--tRNA ligase, mitochondrial, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE (3 entities in total)
• Functional Keywords: trna, serrs, mitochondria, aminoacylation, ligase-rna complex, ligase/rna
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 129672.81

Authors

Hirschi, M.,Kuhle, B.,Doerfel, L.,Schimmel, P.,Lander, G. (deposition date: 2022-02-23, release date: 2022-09-14, Last modification date: 2024-06-12)

• Primary citation: Kuhle, B.,Hirschi, M.,Doerfel, L.K.,Lander, G.C.,Schimmel, P.; Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.; Nat Commun, 13:5100-5100, 2022; PubMed: 36042193; DOI: 10.1038/s41467-022-32544-1

Experimental method

ELECTRON MICROSCOPY (4.1 Å)