8OPT

Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 2

Summary for 8OPT

• Entry DOI: 10.2210/pdb8opt/pdb
• EMDB information: 17087
• Descriptor: Terminal uridylyltransferase 7, RNA (53-MER), Protein lin-28 homolog A, ... (4 entities in total)
• Functional Keywords: polymerase, uridylation, rna maturation and turnover control, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 211860.96

Authors

Yi, G.,Ye, M.,Gilbert, R.J. (deposition date: 2023-04-08, release date: 2024-07-24)

• Primary citation: Yi, G.,Ye, M.,Carrique, L.,El-Sagheer, A.,Brown, T.,Norbury, C.J.,Zhang, P.,Gilbert, R.J.C.; Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs; Nat.Struct.Biol., 2024; DOI: 10.1038/s41594-024-01357-9

Experimental method

ELECTRON MICROSCOPY (3.65 Å)