1VY6

Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site.

This is a large structure.

Summary for 1VY6

Integrates4QCU 4QCV 4QCW 4QCX
Descriptor16S Ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... (60 entities in total)
Functional Keywords70s, ribosome, translation, peptydil transfer reaction, proton transfer mechanism, acylated trna, cytidine-puromycin.
Biological sourceEscherichia coli
More
Total number of polymer chains110
Total molecular weight4447838.78
Authors
Polikanov, Y.S.,Steitz, T.A.,Innis, C.A. (deposition date: 2014-05-13, release date: 2014-08-20, Last modification date: 2015-01-28)
Primary citation
Polikanov, Y.S.,Steitz, T.A.,Innis, C.A.
A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21:787-793, 2014
PubMed: 25132179 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.2871
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.286130.6%11.2%3.2%0.47MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1vy6
no rotation
Molmil generated image of 1vy6
rotated about x axis by 90°
Molmil generated image of 1vy6
rotated about y axis by 90°
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