1VY7

Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site.

Integrates	4QCY 4QCZ 4QD0 4QD1
Descriptor	16S Ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... (61 entities in total)
Functional Keywords	70s, ribosome, translation, peptydil transfer reaction, proton transfer mechanism, acylated trna, cytidine-cytidine-puromycin
Biological source	Escherichia coli More
Total number of polymer chains	112
Total molecular weight	4501050.42
Authors	Polikanov, Y.S.,Steitz, T.A.,Innis, C.A. (deposition date: 2014-05-13, release date: 2014-08-20, Last modification date: 2015-01-28)
Primary citation	Polikanov, Y.S.,Steitz, T.A.,Innis, C.A. A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21:787-793, 2014 PubMed: 25132179 (PDB entries with the same primary citation) DOI: 10.1038/nsmb.2871 Import into Mendeley
Experimental method	X-RAY DIFFRACTION (2.8 Å)