7ZGR

Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA

Summary for 7ZGR

• Entry DOI: 10.2210/pdb7zgr/pdb
• Related: 7ZGP 7ZGQ
• EMDB information: 14710 14711 14712
• Descriptor: Protein CFT1, mRNA 3'-end-processing protein YTH1, Cleavage factor two protein 2, ... (7 entities in total)
• Functional Keywords: cpf, 3'-end processing, rna binding protein
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 6
• Total formula weight: 375548.29

Authors

Rodriguez-Molina, J.B.,Passmore, L.A. (deposition date: 2022-04-04, release date: 2022-05-25, Last modification date: 2022-07-20)

• Primary citation: Rodriguez-Molina, J.B.,O'Reilly, F.J.,Fagarasan, H.,Sheekey, E.,Maslen, S.,Skehel, J.M.,Rappsilber, J.,Passmore, L.A.; Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.; Mol.Cell, 82:2490-, 2022; PubMed: 35584695; DOI: 10.1016/j.molcel.2022.04.021

Experimental method

ELECTRON MICROSCOPY (2.6 Å)