6Q0B
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![BU of 6q0b by Molmil](/molmil-images/mine/6q0b) | Poliovirus (Type 1 Mahoney), receptor-catalysed 135S particle incubated with anti-VP1 mAb at RT for 1 hr | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Hogle, J.M, Filman, D.J, Shah, P.N.M. | Deposit date: | 2019-08-01 | Release date: | 2020-08-05 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate. Plos Pathog., 16, 2020
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5NQ6
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![BU of 5nq6 by Molmil](/molmil-images/mine/5nq6) | Crystal structure of the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE from Escherichia coli at 2.40 Angstrom Resolution | Descriptor: | GLYCEROL, SULFATE ION, Sulfur acceptor protein CsdE | Authors: | Penya-Soler, E, Aranda, J, Lopez-Estepa, M, Gomez, S, Garces, F, Coll, M, Fernandez, F.J, Vega, M.C. | Deposit date: | 2017-04-19 | Release date: | 2018-03-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE. PLoS ONE, 12, 2017
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4LNS
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![BU of 4lns by Molmil](/molmil-images/mine/4lns) | |
7U7N
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![BU of 7u7n by Molmil](/molmil-images/mine/7u7n) | IL-27 quaternary receptor signaling complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | Authors: | Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C. | Deposit date: | 2022-03-07 | Release date: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structure of the IL-27 quaternary receptor signaling complex. Elife, 11, 2022
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1XZP
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![BU of 1xzp by Molmil](/molmil-images/mine/1xzp) | Structure of the GTP-binding protein TrmE from Thermotoga maritima | Descriptor: | Probable tRNA modification GTPase trmE, SULFATE ION | Authors: | Scrima, A, Vetter, I.R, Armengod, M.E, Wittinghofer, A. | Deposit date: | 2004-11-12 | Release date: | 2005-01-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of the TrmE GTP-binding protein and its implications for tRNA modification Embo J., 24, 2005
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6NAJ
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5OUN
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![BU of 5oun by Molmil](/molmil-images/mine/5oun) | NMR solution structure of the external DII domain of Rvb2 from Saccharomyces cerevisiae | Descriptor: | RuvB-like protein 2 | Authors: | Rouillon, C, Bragantini, B, Charpentier, B, Manival, X, Quinternet, M. | Deposit date: | 2017-08-24 | Release date: | 2018-03-28 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | NMR assignment and solution structure of the external DII domain of the yeast Rvb2 protein. Biomol NMR Assign, 12, 2018
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1XZQ
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![BU of 1xzq by Molmil](/molmil-images/mine/1xzq) | Structure of the GTP-binding protein TrmE from Thermotoga maritima complexed with 5-formyl-THF | Descriptor: | N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, Probable tRNA modification GTPase trmE | Authors: | Scrima, A, Vetter, I.R, Armengod, M.E, Wittinghofer, A. | Deposit date: | 2004-11-12 | Release date: | 2005-01-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The structure of the TrmE GTP-binding protein and its implications for tRNA modification Embo J., 24, 2005
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8AXB
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![BU of 8axb by Molmil](/molmil-images/mine/8axb) | Cryo-EM structure of Cas12k-sgRNA binary complex (type V-K CRISPR-associated transposon) | Descriptor: | Cas12k, sgRNA | Authors: | Tenjo-Castano, F, Sofos, N, Stella, S, Molina, R, Pape, T, Lopez-Mendez, B, Stutzke, L.S, Temperini, P, Montoya, G. | Deposit date: | 2022-08-31 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural prediction of the Cas12k interaction with the transposon pre-integration complex To Be Published
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8YR7
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6ERJ
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![BU of 6erj by Molmil](/molmil-images/mine/6erj) | Self-complemented FimA subunit from Salmonella enterica | Descriptor: | ACETIC ACID, Type-1 fimbrial protein, a chain | Authors: | Zyla, D.S, Prota, A, Capitani, G, Glockshuber, R. | Deposit date: | 2017-10-18 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria. J.Biol.Chem., 294, 2019
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2X67
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![BU of 2x67 by Molmil](/molmil-images/mine/2x67) | The ternary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway), tryptophan and cyanide | Descriptor: | CYANIDE ION, PRNB, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Zhu, X, van pee, K.-H, Naismith, J.H. | Deposit date: | 2010-02-15 | Release date: | 2010-03-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | The Ternary Complex of Prnb (the Second Enzyme in Pyrrolnitrin Biosynthesis Pathway), Tryptophan and Cyanide Yields New Mechanistic Insights Into the Indolamine Dioxygenase Superfamily. J.Biol.Chem., 285, 2010
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1CBM
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2X68
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![BU of 2x68 by Molmil](/molmil-images/mine/2x68) | The ternary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway), 7-Cl-L-tryptophan and cyanide | Descriptor: | 7-CHLOROTRYPTOPHAN, CYANIDE ION, PRNB, ... | Authors: | Zhu, X, van pee, K.-H, Naismith, J.H. | Deposit date: | 2010-02-15 | Release date: | 2010-03-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | The Ternary Complex of Prnb (the Second Enzyme in Pyrrolnitrin Biosynthesis Pathway), Tryptophan and Cyanide Yields New Mechanistic Insights Into the Indolamine Dioxygenase Superfamily. J.Biol.Chem., 285, 2010
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1I00
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![BU of 1i00 by Molmil](/molmil-images/mine/1i00) | CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | Authors: | Almog, R.A, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. | Deposit date: | 2001-01-27 | Release date: | 2001-05-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP. Protein Sci., 10, 2001
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6KM7
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![BU of 6km7 by Molmil](/molmil-images/mine/6km7) | The structural basis for the internal interaction in RBBP5 | Descriptor: | HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, Retinoblastoma-binding protein 5, ... | Authors: | Han, J, Li, T, Chen, Y. | Deposit date: | 2019-07-31 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex. Nucleic Acids Res., 47, 2019
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1X3E
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![BU of 1x3e by Molmil](/molmil-images/mine/1x3e) | Crystal structure of the single-stranded DNA-binding protein from Mycobacterium smegmatis | Descriptor: | CADMIUM ION, Single-strand binding protein | Authors: | Saikrishnan, K, Manjunath, G.P, Singh, P, Jeyakanthan, J, Dauter, Z, Sekar, K, Muniyappa, K, Vijayan, M. | Deposit date: | 2005-05-04 | Release date: | 2005-08-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association. Acta Crystallogr.,Sect.D, 61, 2005
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6XVA
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![BU of 6xva by Molmil](/molmil-images/mine/6xva) | Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor bearing an acrylamide | Descriptor: | Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, ~{N}-[[3-[2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanoylamino]-5-methyl-phenyl]methyl]propanamide | Authors: | Schimpl, M, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Ogg, D.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. | Deposit date: | 2020-01-21 | Release date: | 2020-05-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors. J.Am.Chem.Soc., 142, 2020
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4CVQ
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![BU of 4cvq by Molmil](/molmil-images/mine/4cvq) | CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION | Descriptor: | ACETATE ION, GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA, GLYCEROL, ... | Authors: | Penya-Soler, E, Fernandez, F.J, Lopez-Estepa, M, Garces, F, Richardson, A.J, Rudd, K.E, Coll, M, Vega, M.C. | Deposit date: | 2014-03-28 | Release date: | 2014-07-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli. PLoS ONE, 9, 2014
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5E6U
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![BU of 5e6u by Molmil](/molmil-images/mine/5e6u) | Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Sen, M, Springer, T.A. | Deposit date: | 2015-10-10 | Release date: | 2016-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113, 2016
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5E6S
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![BU of 5e6s by Molmil](/molmil-images/mine/5e6s) | Structures of leukocyte integrin aLB2: The aI domain, the headpiece, and the pocket for the internal ligand | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ... | Authors: | Springer, T.A, Sen, M. | Deposit date: | 2015-10-10 | Release date: | 2016-03-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113, 2016
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6XVB
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![BU of 6xvb by Molmil](/molmil-images/mine/6xvb) | Crystal structure of the kinase domain of human c-KIT with a cyclic imidate inhibitor covalently bound to Cys788 | Descriptor: | Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, ~{N}-(4,4-dimethyl-2-propyl-3,1-benzoxazin-6-yl)-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide | Authors: | Schimpl, M, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Ogg, D.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. | Deposit date: | 2020-01-21 | Release date: | 2020-05-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors. J.Am.Chem.Soc., 142, 2020
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1X3G
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![BU of 1x3g by Molmil](/molmil-images/mine/1x3g) | Crystal structure of the single-stranded DNA-binding protein from Mycobacterium SMEGMATIS | Descriptor: | CADMIUM ION, Single-strand binding protein | Authors: | Saikrishnan, K, Manjunath, G.P, Singh, P, Jeyakanthan, J, Dauter, Z, Sekar, K, Muniyappa, K, Vijayan, M. | Deposit date: | 2005-05-05 | Release date: | 2005-08-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association. Acta Crystallogr.,Sect.D, 61, 2005
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4HFW
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![BU of 4hfw by Molmil](/molmil-images/mine/4hfw) | Anti Rotavirus Antibody | Descriptor: | 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION | Authors: | Spiller, B.W, Aiyegbo, M, Crowe, J.E. | Deposit date: | 2012-10-05 | Release date: | 2013-05-29 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore. Plos One, 8, 2013
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7Z1G
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![BU of 7z1g by Molmil](/molmil-images/mine/7z1g) | Crystal structure of nonphosphorylated (Tyr216) GSK3b in complex with CX-4945 | Descriptor: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Glycogen synthase kinase-3 beta, IMIDAZOLE, ... | Authors: | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | Deposit date: | 2022-02-24 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of nonphosphorylated (Tyr216) GSK3b kinase in complex with CX-4945 To Be Published
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