7Z1G

Crystal structure of nonphosphorylated (Tyr216) GSK3b in complex with CX-4945

Summary for 7Z1G

• Entry DOI: 10.2210/pdb7z1g/pdb
• Descriptor: Glycogen synthase kinase-3 beta, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, MALONATE ION, ... (5 entities in total)
• Functional Keywords: kinase, diabetes, kinase inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42502.84

Authors

Grygier, P.,Pustelny, K.,Dubin, G.,Czarna, A. (deposition date: 2022-02-24, release date: 2023-03-08, Last modification date: 2024-02-07)

• Primary citation: Grygier, P.,Pustelny, K.,Golik, P.,Popowicz, G.,Dubin, G.,Czarna, A.; Crystal structure of nonphosphorylated (Tyr216) GSK3b kinase in complex with CX-4945; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.85 Å)