5E6S

Structures of leukocyte integrin aLB2: The aI domain, the headpiece, and the pocket for the internal ligand

Summary for 5E6S

Related5E6R 5E6U
DescriptorIntegrin alpha-L, Integrin beta-2, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordslymphocyte function-associated antigen-1, cell adhesion
Biological sourceHomo sapiens (Human)
Cellular locationCell membrane ; Single-pass type I membrane protein  P20701
Membrane; Single-pass type I membrane protein P05107
Total number of polymer chains6
Total molecular weight436887.64
Authors
Springer, T.A.,Sen, M. (deposition date: 2015-10-10, release date: 2016-03-02, Last modification date: 2017-09-27)
Primary citation
Sen, M.,Springer, T.A.
Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113:2940-2945, 2016
PubMed: 26936951 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1601379113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.15 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23450.3%1.0%7.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5e6s
no rotation
Molmil generated image of 5e6s
rotated about x axis by 90°
Molmil generated image of 5e6s
rotated about y axis by 90°