Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand

Summary for 5E6U

Related5E6S 5E6R 5E6W 5E6X
DescriptorIntegrin alpha-L, Integrin beta-2, MAGNESIUM ION, ... (7 entities in total)
Functional Keywordslymphocyte function-associated antigen-1, lfa-1, cell adhesion
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight145648.89
Sen, M.,Springer, T.A. (deposition date: 2015-10-10, release date: 2016-04-06, Last modification date: 2020-07-29)
Primary citation
Sen, M.,Springer, T.A.
Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113:2940-2945, 2016
PubMed: 26936951 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1601379113
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2266 0.2% 1.0% 5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21