Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit

Summary for 5E6W

DescriptorIntegrin beta-2, N-ACETYL-D-GLUCOSAMINE (3 entities in total)
Functional Keywordscd18 fragment, cell adhesion
Biological sourceHomo sapiens (Human)
Cellular locationMembrane; Single-pass type I membrane protein P05107
Total number of polymer chains1
Total molecular weight35340.87
Springer, T.A.,Sen, M. (deposition date: 2015-10-10, release date: 2016-03-02, Last modification date: 2017-09-27)
Primary citation
Sen, M.,Springer, T.A.
Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113:2940-2945, 2016
PubMed: 26936951 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1601379113
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27090.7%4.1%13.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5e6w
no rotation
Molmil generated image of 5e6w
rotated about x axis by 90°
Molmil generated image of 5e6w
rotated about y axis by 90°