5E6W

Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0007160	biological_process	cell-matrix adhesion
A	0007229	biological_process	integrin-mediated signaling pathway
A	0008305	cellular_component	integrin complex
A	0038023	molecular_function	signaling receptor activity

Functional Information from PROSITE/UniProt

site_id	PS00243
Number of Residues	14
Details	INTEGRIN_BETA Integrins beta chain cysteine-rich domain signature. CsGl..GdCvCgqClC

Chain	Residue	Details
A	CYS484-CYS497
A	CYS527-CYS542

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site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CrCdtGyiGKnC

Chain	Residue	Details
A	CYS448-CYS459
A	CYS540-CYS551

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site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. CrCdtGYigknce..C

Chain	Residue	Details
A	CYS448-CYS461
A	CYS540-CYS551

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000305|PubMed:2954816

Chain	Residue	Details
A	GLN1

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASN28

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:20033057, ECO:0000269|PubMed:24385486, ECO:0007744|PDB:4NEH, ECO:0007744|PDB:4NEN

Chain	Residue	Details
A	ASN94

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN479

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