1I00

CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX

Summary for 1I00

• Entry DOI: 10.2210/pdb1i00/pdb
• Related: 1HZW
• Descriptor: THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, ... (4 entities in total)
• Functional Keywords: thymidylate synthase, human, ternary complex, dump, tomudex, open conformation, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P04818
• Total number of polymer chains: 2
• Total formula weight: 67911.48

Authors

Almog, R.A.,Waddling, C.A.,Maley, F.,Maley, G.F.,Van Roey, P. (deposition date: 2001-01-27, release date: 2001-05-09, Last modification date: 2023-08-09)

• Primary citation: Almog, R.,Waddling, C.A.,Maley, F.,Maley, G.F.,Van Roey, P.; Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.; Protein Sci., 10:988-996, 2001; PubMed: 11316879; DOI: 10.1110/ps.47601

Experimental method

X-RAY DIFFRACTION (2.5 Å)