8YR7

Crystal structure of human dishevelled 2 (Dvl2) PDZ domain fused with WGEF internal peptide motif

Summary for 8YR7

Entry DOI	10.2210/pdb8yr7/pdb
Descriptor	Segment polarity protein dishevelled homolog DVL-2,Rho guanine nucleotide exchange factor 19 (1 entity in total)
Functional Keywords	wnt signaling, signaling protein
Biological source	synthetic construct More
Total number of polymer chains	1
Total formula weight	11607.19
Authors	Omble, A.,Mahajan, S.,Kulkarni, K.A. (deposition date: 2024-03-20, release date: 2024-05-29)
Primary citation	Omble, A.,Mahajan, S.,Bhoite, A.,Kulkarni, K. Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF. Commun Biol, 7:543-543, 2024 Cited by PubMed: 38714795 DOI: 10.1038/s42003-024-06194-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation