4HFW

Anti Rotavirus Antibody

Summary for 4HFW

Descriptor6-26 Fab Light chain, 6-26 Fab Heavy chain, SULFATE ION, ... (4 entities in total)
Functional Keywordsig fold, immune response, rotavirus vp6 protein, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total molecular weight94503.35
Authors
Spiller, B.W.,Aiyegbo, M.,Crowe, J.E. (deposition date: 2012-10-05, release date: 2013-05-29)
Primary citation
Aiyegbo, M.S.,Sapparapu, G.,Spiller, B.W.,Eli, I.M.,Williams, D.R.,Kim, R.,Lee, D.E.,Liu, T.,Li, S.,Woods, V.L.,Nannemann, D.P.,Meiler, J.,Stewart, P.L.,Crowe, J.E.
Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8:e61101-e61101, 2013
PubMed: 23671563 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0061101
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.601 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.234803.0%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution