4E3Q
| PMP-bound form of Aminotransferase crystal structure from Vibrio fluvialis | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BENZAMIDINE, Pyruvate transaminase, ... | Authors: | Midelfort, K.S, Kumar, R, Han, S, Karmilowicz, M.J, McConnell, K, Gehlhaar, D.K, Mistry, A, Chang, J.S, Anderson, M, Vilalobos, A, Minshull, J, Govindarajan, S, Wong, J.W. | Deposit date: | 2012-03-10 | Release date: | 2012-10-10 | Last modified: | 2013-01-02 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. Protein Eng.Des.Sel., 26, 2013
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4E6P
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6DWH
| Crystal structure of complex of BBKI and Bovine Trypsin | Descriptor: | CHLORIDE ION, Cationic trypsin, Kunitz-type inihibitor, ... | Authors: | Li, M, Wlodawer, A. | Deposit date: | 2018-06-26 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the complex of a kallikrein inhibitor from Bauhinia bauhinioides with trypsin and modeling of kallikrein complexes. Acta Crystallogr D Struct Biol, 75, 2019
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6DMD
| ppGpp Riboswitch bound to ppGpp, manganese chloride structure | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Peselis, A, Serganov, A. | Deposit date: | 2018-06-05 | Release date: | 2018-11-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
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4WXG
| Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine | Descriptor: | GLYCEROL, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, SODIUM ION, ... | Authors: | Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P. | Deposit date: | 2014-11-13 | Release date: | 2015-02-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids. Angew.Chem.Int.Ed.Engl., 54, 2015
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4WZI
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4WR8
| Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180) | Descriptor: | 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ... | Authors: | Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. | Deposit date: | 2014-10-23 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
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4LP4
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7A5F
| Structure of the stalled human mitoribosome with P- and E-site mt-tRNAs | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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6ZPQ
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4LRT
| Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site | Descriptor: | 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, COENZYME A, ... | Authors: | Fischer, B, Branlant, G, Talfournier, F, Gruez, A. | Deposit date: | 2013-07-20 | Release date: | 2013-09-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site To be Published
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4X5L
| Crystal structure of Dscam1 Ig7 domain, isoform 9 | Descriptor: | Down syndrome cell adhesion molecule, isoform AM, SODIUM ION | Authors: | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | Deposit date: | 2014-12-05 | Release date: | 2015-12-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.374 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4M4S
| Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDP and formate ion mimic aIF2gamma*GDP*Pi complex (a formate ion substitutes for Pi) | Descriptor: | FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nikonov, O.S, Stolboushkina, E.A, Arkhipova, V.I, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V. | Deposit date: | 2013-08-07 | Release date: | 2014-03-12 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2. Acta Crystallogr.,Sect.D, 70, 2014
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5EPU
| X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytosine at 1.06A. | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-AMINOPYRIMIDIN-2(1H)-ONE, ... | Authors: | Prokofev, I.I, Lashkov, A.A, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M. | Deposit date: | 2015-11-12 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytosine at 1.06A. To Be Published
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2FI3
| Crystal structure of a BPTI variant (Cys14->Ser, Cys38->Ser) in complex with trypsin | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2005-12-27 | Release date: | 2006-01-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. J.Mol.Biol., 382, 2008
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2FI5
| Crystal structure of a BPTI variant (Cys38->Ser) in complex with trypsin | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2005-12-27 | Release date: | 2006-01-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. J.Mol.Biol., 382, 2008
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2FTL
| Crystal structure of trypsin complexed with BPTI at 100K | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2006-01-24 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin. J.Mol.Biol., 366, 2007
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2FTM
| Crystal structure of trypsin complexed with the BPTI variant (Tyr35->Gly) | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2006-01-24 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin. J.Mol.Biol., 366, 2007
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4W9N
| Enoyl-acyl carrier protein-reductase domain from human fatty acid synthase complexed with triclosan | Descriptor: | CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase, IMIDAZOLE, ... | Authors: | Sippel, K.H, Vyas, N.K, Sankaran, B, Quiocho, F.A. | Deposit date: | 2014-08-27 | Release date: | 2014-10-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition. J.Biol.Chem., 289, 2014
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3STH
| Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Toxoplasma gondii | Descriptor: | 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Seattle Structural Genomics Center for Infectious Disease (SSGCID), Staker, B.L, Edwards, T.E, Sankaran, B. | Deposit date: | 2011-07-10 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Membrane skeletal association and post-translational allosteric regulation of Toxoplasma gondii GAPDH1. Mol.Microbiol., 103, 2017
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3SXQ
| Structure of a hexameric multiheme c nitrite reductase from the extremophile bacterium Thiolkalivibrio paradoxus | Descriptor: | CALCIUM ION, CHLORIDE ION, COBALT (II) ION, ... | Authors: | Polyakov, K.M, Trofimov, A.A, Tikhonova, T.V, Tikhonov, A.V, Boyko, K.M, Popov, V.O. | Deposit date: | 2011-07-15 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Comparative structural and functional analysis of two octaheme nitrite reductases from closely related Thioalkalivibrio species. Febs J., 279, 2012
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3T46
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6DJQ
| Vps1 GTPase-BSE fusion complexed with GDP.AlF4- | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | Authors: | Varlakhanova, N.V, Brady, T.M, Tornabene, B.A, Hosford, C.J, Chappie, J.S, Ford, M.G.J. | Deposit date: | 2018-05-25 | Release date: | 2018-08-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture. J. Cell Biol., 217, 2018
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6KTR
| Crystal structure of fibroblast growth factor 19 in complex with Fab | Descriptor: | Fibroblast growth factor 19, G1A8-Fab-HC, G1A8-Fab-LC, ... | Authors: | Liu, H, Zheng, S, Hou, X, Liu, X, Lv, X, Li, Y, Li, W, Sui, J. | Deposit date: | 2019-08-28 | Release date: | 2020-07-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.59775758 Å) | Cite: | Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Cancer Sci., 111, 2020
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3SVW
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