6KTR
Crystal structure of fibroblast growth factor 19 in complex with Fab
Summary for 6KTR
Entry DOI | 10.2210/pdb6ktr/pdb |
Descriptor | G1A8-Fab-HC, G1A8-Fab-LC, Fibroblast growth factor 19, ... (6 entities in total) |
Functional Keywords | complex, growth factor, antibody, cell cycle, immune system-protein binding complex, immune system/protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 145328.46 |
Authors | |
Primary citation | Liu, H.,Zheng, S.,Hou, X.,Liu, X.,Du, K.,Lv, X.,Li, Y.,Yang, F.,Li, W.,Sui, J. Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Cancer Sci., 111:1750-1760, 2020 Cited by PubMed: 32061104DOI: 10.1111/cas.14353 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59775753879 Å) |
Structure validation
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