Crystal structure of a BPTI variant (Cys38->Ser) in complex with trypsin

Summary for 2FI5

Related2PTC 2FI3 2FI4
DescriptorCationic trypsin, Pancreatic trypsin inhibitor, SODIUM ION, ... (7 entities in total)
Functional Keywordsprotease-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceBos taurus
Total number of polymer chains2
Total molecular weight31142.9
Zakharova, E.,Horvath, M.P.,Goldenberg, D.P. (deposition date: 2005-12-27, release date: 2006-01-24, Last modification date: 2018-08-29)
Primary citation
Zakharova, E.,Horvath, M.P.,Goldenberg, D.P.
Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382:998-1013, 2008
PubMed: 18692070 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2008.07.063
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.236500.4%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report