2FI3

Crystal structure of a BPTI variant (Cys14->Ser, Cys38->Ser) in complex with trypsin

Summary for 2FI3
Related2FI4 2FI5 2PTC
DescriptorCationic trypsin, Pancreatic trypsin inhibitor, SODIUM ION, ... (7 entities in total)
Functional Keywordsprotease-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceBos taurus (cattle)
More
Cellular locationSecreted, extracellular space: P00760
Secreted: P00974
Total number of polymer chains2
Total formula weight31063.78
Authors
Zakharova, E.,Horvath, M.P.,Goldenberg, D.P. (deposition date: 2005-12-27, release date: 2006-01-24, Last modification date: 2011-07-13)
Primary citationGoldenberg, D.P.,Horvath, M.P.,Zakharova, E.
Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382:998-1013, 2008
PubMed: 18692070
DOI: 110.1016/j.jmb.2008.07.063
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.58 Å)
Structure validation
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178938

PDB entries from 2021-06-16