2FTL
Crystal structure of trypsin complexed with BPTI at 100K
Summary for 2FTL
Entry DOI | 10.2210/pdb2ftl/pdb |
Related | 2FTM 2PTC |
Descriptor | Cationic trypsin, Pancreatic trypsin inhibitor, SODIUM ION, ... (7 entities in total) |
Functional Keywords | protease-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00760 Secreted: P00974 |
Total number of polymer chains | 2 |
Total formula weight | 31096.90 |
Authors | Hanson, W.M.,Horvath, M.P.,Goldenberg, D.P. (deposition date: 2006-01-24, release date: 2006-02-14, Last modification date: 2023-08-30) |
Primary citation | Hanson, W.M.,Domek, G.J.,Horvath, M.P.,Goldenberg, D.P. Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin. J.Mol.Biol., 366:230-243, 2007 Cited by PubMed: 17157870DOI: 10.1016/j.jmb.2006.11.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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