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8PX0
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BU of 8px0 by Molmil
Structure of ribonuclease A, solved at wavelength 2.75 A
Descriptor: L-URIDINE-5'-MONOPHOSPHATE, Ribonuclease pancreatic
Authors:El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Romano, M, Beis, K, Wagner, A.
Deposit date:2023-07-22
Release date:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8K5C
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BU of 8k5c by Molmil
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Human hydroxycarboxylic acid receptor 2
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5D
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BU of 8k5d by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Human hydroxycarboxylic acid receptor 2
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5B
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BU of 8k5b by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: Human Hydroxycarboxylic acid receptor 2, NICOTINIC ACID
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K53
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BU of 8k53 by Molmil
Structure of the Dimeric Human CNTN2 Ig 1-6-FNIII 1-2 Domain in an Asymmetric State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ...
Authors:Zhang, Z.Z.
Deposit date:2023-07-21
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of human CNTN2 immunoglobulin domains 1-6 homo-dimer
To Be Published
8K4N
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BU of 8k4n by Molmil
Structure of GPR34-Gi complex
Descriptor: (2R)-2-azanyl-3-[oxidanyl-[(2R)-2-oxidanyl-3-tetradec-9-enoyloxy-propoxy]phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wong, T.S, Zeng, Z.C, Xiong, T.T, Gan, S.Y, He, G.D, Du, Y.
Deposit date:2023-07-20
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Cryo-EM structure of GPR34-Gi complex
To Be Published
8PWN
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BU of 8pwn by Molmil
Structure of A2A adenosine receptor A2AR-StaR2-bRIL, solved at wavelength 2.75 A
Descriptor: Adenosine receptor A2a,Soluble cytochrome b562, CHOLESTEROL, OLEIC ACID, ...
Authors:El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Romano, M, Moraes, I, Wagner, A.
Deposit date:2023-07-20
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8TID
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BU of 8tid by Molmil
Combined linker domain of N-DRC and associated proteins Tetrahymena
Descriptor: AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ...
Authors:Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H.
Deposit date:2023-07-19
Release date:2023-09-27
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8PW7
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BU of 8pw7 by Molmil
A respirasome from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-07-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8PW5
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BU of 8pw5 by Molmil
CS respirasome from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-07-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8PW6
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BU of 8pw6 by Molmil
C respirasome from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-07-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8TI1
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BU of 8ti1 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TI2
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BU of 8ti2 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TI0
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BU of 8ti0 by Molmil
ATP-1 state of Bcs1 (unsymmetrized)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-07-18
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8PVP
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BU of 8pvp by Molmil
Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FGJG18
Descriptor: CSNK2A1 protein, SULFATE ION, ~{N}-[5-[(3-chloranyl-4-phenyl-phenyl)methylamino]pentyl]isoquinoline-5-sulfonamide
Authors:Kraemer, A, Greco, F, Gerninghaus, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-07-18
Release date:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FGJG18
To Be Published
8PVO
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BU of 8pvo by Molmil
Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FG5
Descriptor: 1,2-ETHANEDIOL, 2-[1-(1,3-benzothiazol-6-ylsulfonyl)piperidin-4-yl]-~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]ethanamine, CSNK2A1 protein, ...
Authors:Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-07-18
Release date:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FG5
To Be Published
8THL
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BU of 8thl by Molmil
Cryo-EM structure of epinephrine-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
Descriptor: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Su, M, Huang, X.Y.
Deposit date:2023-07-17
Release date:2023-08-16
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023
8THK
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BU of 8thk by Molmil
Cryo-EM structure of A61603-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
Descriptor: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Su, M, Huang, X.Y.
Deposit date:2023-07-17
Release date:2023-08-16
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023
8K3Y
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BU of 8k3y by Molmil
The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease
Authors:Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I.
Deposit date:2023-07-17
Release date:2023-10-25
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (4.42 Å)
Cite:A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
8K4B
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BU of 8k4b by Molmil
Cryo-EM structure of nucleotide-bound ComA with ZinC ion
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA, ZINC ION
Authors:Yu, L, Xin, X, Min, L, Feng, H.
Deposit date:2023-07-17
Release date:2023-10-11
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8THP
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BU of 8thp by Molmil
PorX phosphatase null mutant (T271V)
Descriptor: CALCIUM ION, GLYCEROL, Response regulator receiver protein
Authors:Saran, A, Zeytuni, N.
Deposit date:2023-07-17
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:PorX phosphatase null mutant (T271V)
To Be Published
8PUH
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BU of 8puh by Molmil
Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-CTD refinement
Descriptor: Gag polyprotein
Authors:Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M.
Deposit date:2023-07-17
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
8PUG
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BU of 8pug by Molmil
Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-NTD refinement
Descriptor: Gag polyprotein
Authors:Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M.
Deposit date:2023-07-17
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
8PUQ
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BU of 8puq by Molmil
MetHemoglobin structure from serial synchrotron crystallography with fixed target
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bjelcic, M, Sigfridsson Clauss, K, Aurelius, O, Milas, M, Nan, J, Ursby, T.
Deposit date:2023-07-17
Release date:2023-10-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Anaerobic fixed-target serial crystallography using sandwiched silicon nitride membranes.
Acta Crystallogr D Struct Biol, 79, 2023
8PUR
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BU of 8pur by Molmil
DexyHemoglobin structure from serial synchrotron crystallography with fixed target
Descriptor: Hemoglobin subunit beta, Hemoglobin, alpha 1, ...
Authors:Bjelcic, M, Sigfridsson Clauss, K, Aurelius, O, Milas, M, Nan, J, Ursby, T.
Deposit date:2023-07-17
Release date:2023-10-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Anaerobic fixed-target serial crystallography using sandwiched silicon nitride membranes.
Acta Crystallogr D Struct Biol, 79, 2023

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PDB entries from 2024-07-10

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