8K3Y

The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant

Summary for 8K3Y

Entry DOI	10.2210/pdb8k3y/pdb
EMDB information	36867
Descriptor	Lon protease, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	aaa+ protein, atpase, hydrolase
Biological source	Meiothermus taiwanensis More
Total number of polymer chains	6
Total formula weight	511430.99
Authors	Li, S.,Hsieh, K.Y.,Kuo, C.I.,Zhang, K.,Chang, C.I. (deposition date: 2023-07-17, release date: 2023-10-25, Last modification date: 2023-11-29)
Primary citation	Li, S.,Hsieh, K.Y.,Kuo, C.I.,Lin, T.C.,Lee, S.H.,Chen, Y.R.,Wang, C.H.,Ho, M.R.,Ting, S.Y.,Zhang, K.,Chang, C.I. A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14:7340-7340, 2023 Cited by PubMed: 37957149 DOI: 10.1038/s41467-023-43035-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.42 Å)

Structure validation