8K3Y
The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Lon protease | polymer | 799 | 89307.4 | 5 | UniProt (A0A059VAZ3) Pfam (PF02190) Pfam (PF00004) Pfam (PF05362) In PDB | Meiothermus taiwanensis | ATP-dependent protease La |
2 | F | Lon protease | polymer | 570 | 63185.3 | 1 | UniProt (A0A059VAZ3) Pfam (PF00004) Pfam (PF05362) In PDB | Meiothermus taiwanensis | ATP-dependent protease La |
3 | B, C, D, E | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) |
Sequence modifications
A, B, C, D, E: 1 - 793 (UniProt: A0A059VAZ3)
F: 242 - 793 (UniProt: A0A059VAZ3)
PDB | External Database | Details |
---|---|---|
Ser 224 | Tyr 224 | engineered mutation |
His 794 | - | expression tag |
His 795 | - | expression tag |
His 796 | - | expression tag |
His 797 | - | expression tag |
His 798 | - | expression tag |
His 799 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His 224 | - | expression tag |
His 225 | - | expression tag |
His 226 | - | expression tag |
His 227 | - | expression tag |
His 228 | - | expression tag |
His 229 | - | expression tag |
Ser 230 | - | expression tag |
Ser 231 | - | expression tag |
Gly 232 | - | expression tag |
Glu 233 | - | expression tag |
Asn 234 | - | expression tag |
Leu 235 | - | expression tag |
Tyr 236 | - | expression tag |
Phe 237 | - | expression tag |
Gln 238 | - | expression tag |
Gly 239 | - | expression tag |
His 240 | - | expression tag |
Met 241 | - | expression tag |
Lys 613 | Glu 613 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 509722.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1708.8 | |
All* | Total formula weight | 511431.0 |