4ZXB
| Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Croll, T, Smith, B.J, Margetts, M.B, Whittaker, J, Weiss, M.A, Ward, C.W, Lawrence, M.C. | Deposit date: | 2015-05-20 | Release date: | 2016-02-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain. Structure, 24, 2016
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4H1L
| TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy | Descriptor: | Ani2.3 TCR A chain, Ani2.3 TCR B chain, HLA class II histocompatibility antigen, ... | Authors: | Kappler, J.W, Yin, L, Dai, S, Marrack, P. | Deposit date: | 2012-09-10 | Release date: | 2012-11-14 | Last modified: | 2013-09-04 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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4HDI
| Crystal Structure of 3E5 IgG3 FAB from mus musculus | Descriptor: | Ig heavy chain V region RF, Ig gamma-3 chain C region, Kappa light chain variable region, ... | Authors: | Janda, A, Eryilmaz, E, Kim, J, Cordero, R.J.B, Cowburn, D, Casadevall, A. | Deposit date: | 2012-10-02 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.449 Å) | Cite: | Global structures of IgG isotypes expressing identical variable regions. Mol.Immunol., 56, 2013
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5WKI
| Crystal structure of PG90 TCR-CD1b-PG complex | Descriptor: | (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shahine, A, Gras, S, Rossjohn, J. | Deposit date: | 2017-07-25 | Release date: | 2017-11-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Sci Immunol, 2, 2017
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5WKO
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5WHJ
| Crystal structure of Fab fragment of anti-FcRn antibody DX-2507 | Descriptor: | DX-2507 Fab heavy chain, DX-2507 Fab light chain | Authors: | Edwards, T.E, Fairman, J.W, Nixon, A.E, Kenniston, J.A. | Deposit date: | 2017-07-17 | Release date: | 2017-09-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody. J. Biol. Chem., 292, 2017
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5WER
| Crystal Structure of TAPBPR and H2-Dd complex | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CITRIC ACID, ... | Authors: | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2017-07-10 | Release date: | 2017-10-18 | Last modified: | 2019-08-28 | Method: | X-RAY DIFFRACTION (3.412 Å) | Cite: | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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5WHK
| Crystal structure of Fab fragment of antibody DX-2507 bound to FcRn-B2M | Descriptor: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, ... | Authors: | Edwards, T.E, Clifton, M.C, Nixon, A.E, Kenniston, J.A. | Deposit date: | 2017-07-17 | Release date: | 2017-09-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody. J. Biol. Chem., 292, 2017
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5WLG
| Crystal Structure of H-2Db with the GAP501 peptide (SQL) | Descriptor: | Beta-2-microglobulin, CHLORIDE ION, GAP50 peptide, ... | Authors: | Gras, S, Farenc, C, Josephs, T, Rossjohn, J. | Deposit date: | 2017-07-26 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene. Immunity, 47, 2017
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5X5W
| Crystal structure of pseudorabies virus glycoprotein D | Descriptor: | GD, Nectin-1 | Authors: | Li, A, Lu, G, Qi, J, Wu, L, Tian, K, Luo, T, Shi, Y, Yan, J, Gao, G.F. | Deposit date: | 2017-02-17 | Release date: | 2017-04-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of pseudorabies virus glycoprotein D To Be Published
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5XRQ
| Crystal structure of human monoclonal antibody H3v-47 | Descriptor: | Fab H3v-47 heavy chain, Fab H3v-47 light chain | Authors: | Zhang, H, Willson, I.A. | Deposit date: | 2017-06-09 | Release date: | 2018-07-25 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018
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5XSY
| Structure of the Nav1.4-beta1 complex from electric eel | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein, Voltage-gated sodium channel beta subunit 1, ... | Authors: | Yan, Z, Zhou, Q, Wu, J.P, Yan, N. | Deposit date: | 2017-06-15 | Release date: | 2017-08-09 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of the Nav1.4-beta 1 Complex from Electric Eel. Cell, 170, 2017
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5WKZ
| VH1-69 germline antibody predicted from CR6261 | Descriptor: | Immunoglobulin heavy variable 1-69D,IgG H chain, Lambda-chain (AA -20 to 215), SULFATE ION | Authors: | Lang, S, Lee, P.S. | Deposit date: | 2017-07-25 | Release date: | 2018-08-01 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem To Be Published
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6D78
| The complex between high-affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(27-35)peptide | Descriptor: | Beta-2-microglobulin, DMF5 alpha chain,DMF5 alpha chain, DMF5 beta chain,DMF5 beta chain, ... | Authors: | Hellman, L.M, Singh, N.K. | Deposit date: | 2018-04-24 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.347 Å) | Cite: | Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Mol. Ther., 27, 2019
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6DKP
| The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide | Descriptor: | Beta-2-microglobulin, DMF5 T-cell Receptor Alpha Chain fusion, DMF5 T-cell Receptor Beta Chain fusion, ... | Authors: | Hellman, L.M, Singh, N.K. | Deposit date: | 2018-05-30 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.966 Å) | Cite: | Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Mol. Ther., 27, 2019
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6DC4
| RSV-neutralizing human antibody AM22 | Descriptor: | 1,2-ETHANEDIOL, Fab AM22 Heavy Chain, Fab AM22 Light Chain | Authors: | Jones, H.G, McLellan, J.S. | Deposit date: | 2018-05-04 | Release date: | 2019-07-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
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6DC3
| RSV prefusion F bound to RSD5 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ... | Authors: | Battles, M.B, McLellan, J.S, Jones, H.J. | Deposit date: | 2018-05-04 | Release date: | 2019-07-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
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6DID
| HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B. | Deposit date: | 2018-05-23 | Release date: | 2018-09-05 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.71 Å) | Cite: | Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity, 49, 2018
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6DLD
| Crystal structure of IgLON5/NEGR1 heterodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IgLON family member 5, Neuronal growth regulator 1, ... | Authors: | Ranaivoson, F.M, Turk, L.S, Ozkan, E, Montelione, G.T, Comoletti, D. | Deposit date: | 2018-06-01 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of a heterodimer of neuronal cell surface proteins Structure, 2019
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6DC5
| RSV prefusion F in complex with AM22 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Jones, H.G, McLellan, J.S. | Deposit date: | 2018-05-04 | Release date: | 2019-07-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
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6DKJ
| human GIPR ECD and Fab complex | Descriptor: | 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... | Authors: | Min, X, Wang, Z. | Deposit date: | 2018-05-29 | Release date: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models. Sci Transl Med, 10, 2018
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6E9I
| The crystal structure of bovine ultralong antibody BOV-4 | Descriptor: | Bovine ultralong antibody BOV-4 heavy chain, Bovine ultralong antibody BOV-4 light chain | Authors: | Dong, J, Crowe, J.E. | Deposit date: | 2018-08-01 | Release date: | 2019-05-01 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains. Front Immunol, 10, 2019
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6E9G
| The crystal structure of bovine ultralong antibody BOV-2 | Descriptor: | Bovine ultralong antibody BOV-2 heavy chain, Bovine ultralong antibody BOV-2 light chain | Authors: | Dong, J, Crowe, J.E. | Deposit date: | 2018-08-01 | Release date: | 2019-05-01 | Method: | X-RAY DIFFRACTION (2.904 Å) | Cite: | Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains. Front Immunol, 10, 2019
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6EG0
| Crystal structure of Dpr4 Ig1-Ig2 in complex with DIP-Eta Ig1-Ig3 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Cosmanescu, F, Shapiro, L. | Deposit date: | 2018-08-17 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron, 100, 2018
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6E9K
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