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PDB: 57 results

6RXD
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BU of 6rxd by Molmil
Crystal Structure of Bifidobacterium longum Multiple Inositol Polyphosphate Phosphatase Apo Form
Descriptor: Histidine acid phosphatase, ZINC ION
Authors:Li, A.W.H, Brearley, C.A, Hemmings, A.M.
Deposit date:2019-06-07
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism.
J.Biol.Chem., 295, 2020
7QAZ
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BU of 7qaz by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, COBALT (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-11-17
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
7NQF
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BU of 7nqf by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 with dsDNA
Descriptor: COBALT (II) ION, DNA(CGTGDG), TPR_REGION domain-containing protein
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-03-01
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
7P9J
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BU of 7p9j by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, COBALT (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-07-27
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
7NQD
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BU of 7nqd by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137
Descriptor: TPR_REGION domain-containing protein
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-03-01
Release date:2022-05-04
Last modified:2022-06-08
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
7NQE
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BU of 7nqe by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 with dGTP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-03-01
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
8BGJ
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BU of 8bgj by Molmil
Crystal structure of Reverse Transcriptase domain from Caloramator australicus CART-CAPP
Descriptor: L(+)-TARTARIC ACID, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2022-10-27
Release date:2023-06-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
5HY6
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BU of 5hy6 by Molmil
Spodoptera frugiperda eukaryotic translation initiation factor EIF5A
Descriptor: Eukaryotic translation initiation factor 5A
Authors:Li, A.W.H, Oliver, A.W, Pearl, L.H.
Deposit date:2016-02-01
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.186 Å)
Cite:Structure of Spodoptera frugiperda eukaryotic translation initiation factor EIF5A
To Be Published
5CU7
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BU of 5cu7 by Molmil
Bacteroides Thetaiotaomicron Multiple Inositol Polyphosphate Phosphatase A324D Mutant
Descriptor: PHOSPHATE ION, multiple inositol polyphosphate histidine phosphatase 1
Authors:Li, A.W.H, Hemmings, A.M.
Deposit date:2015-07-24
Release date:2016-08-17
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The Hydrolytic Positional Specificity Towards Phytic Acid of a Bacterial Multiple Inositol Polyphosphate Phosphatase
To be published
8H4P
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BU of 8h4p by Molmil
class I sesquiterpene synthase
Descriptor: Longiborneol synthase CLM1, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ...
Authors:Li, A.N, Lou, T.T, Ma, M.
Deposit date:2022-10-11
Release date:2023-08-23
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis.
J.Am.Chem.Soc., 2023
5CX4
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BU of 5cx4 by Molmil
Crystal Structure of a Multiple Inositol Polyphosphate Phosphatase
Descriptor: PHOSPHATE ION, multiple inositol polyphosphate histidine phosphatase 1
Authors:Li, A.W.H, Hemmings, A.M.
Deposit date:2015-07-28
Release date:2016-08-17
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The Hydrolytic Positional Specificity Towards Phytic Acid of a Bacterial Multiple Inositol Polyphosphate Phosphatase
To be published
4FDU
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BU of 4fdu by Molmil
Crystal Structure of a Multiple Inositol Polyphosphate Phosphatase
Descriptor: 1,2-ETHANEDIOL, D-MYO-INOSITOL-HEXASULPHATE, Putative multiple inositol polyphosphate histidine phosphatase 1
Authors:Li, A.W.H, Hemmings, A.M.
Deposit date:2012-05-29
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut.
Cell Rep, 6, 2014
4FDT
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BU of 4fdt by Molmil
Crystal Structure of a Multiple Inositol Polyphosphate Phosphatase
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, Putative multiple inositol polyphosphate histidine phosphatase 1
Authors:Li, A.W.H, Hemmings, A.M.
Deposit date:2012-05-29
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut.
Cell Rep, 6, 2014
3RV5
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BU of 3rv5 by Molmil
Crystal structure of human cardiac troponin C regulatory domain in complex with cadmium and deoxycholic acid
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, CADMIUM ION, CALCIUM ION, ...
Authors:Li, A.Y, Lee, J, Borek, D, Otwinowski, Z, Tibbits, G, Paetzel, M.
Deposit date:2011-05-06
Release date:2011-08-31
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of cardiac troponin C regulatory domain in complex with cadmium and deoxycholic Acid reveals novel conformation.
J.Mol.Biol., 413, 2011
5X5W
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BU of 5x5w by Molmil
Crystal structure of pseudorabies virus glycoprotein D
Descriptor: GD, Nectin-1
Authors:Li, A, Lu, G, Qi, J, Wu, L, Tian, K, Luo, T, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2017-02-17
Release date:2017-04-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of pseudorabies virus glycoprotein D
To Be Published
8BAO
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BU of 8bao by Molmil
Dysgonamonadaceae bacterium CRISPR ancillary nuclease 2
Descriptor: BROMIDE ION, Cyclic tetra-adenylate (cA4), DUF1887 family protein, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2022-10-11
Release date:2022-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
5X5V
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BU of 5x5v by Molmil
Crystal structure of pseudorabies virus glycoprotein D
Descriptor: GD
Authors:Li, A, Lu, G, Qi, J, Wu, L, Tian, K, Luo, T, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2017-02-17
Release date:2017-04-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of pseudorabies virus glycoprotein D
To Be Published
4WHG
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BU of 4whg by Molmil
Crystal Structure of TR3 LBD in complex with Molecule 3
Descriptor: 1-(3,4,5-trihydroxyphenyl)octan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
Authors:Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Wang, Y, Hou, P.P, Wu, Q, Lin, T.W.
Deposit date:2014-09-22
Release date:2015-09-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
4WHF
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BU of 4whf by Molmil
Crystal Structure of TR3 LBD in complex with 1-(3,4,5-trihydroxyphenyl)decan-1-one
Descriptor: 1-(3,4,5-trihydroxyphenyl)decan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
Authors:Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Wang, Y, Hou, P.P, Wu, Q, Lin, T.W.
Deposit date:2014-09-22
Release date:2015-09-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
7SSE
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BU of 7sse by Molmil
Crystal structure of the WDR domain of human DCAF1 in complex with CYCA-117-70
Descriptor: DDB1- and CUL4-associated factor 1, N-[(3R)-1-(3-fluorophenyl)piperidin-3-yl]-6-(morpholin-4-yl)pyrimidin-4-amine
Authors:Kimani, S, Owen, J, Li, A, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Shahani, V.M, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
Deposit date:2021-11-10
Release date:2021-12-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets.
J.Chem.Inf.Model., 63, 2023
4RZF
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BU of 4rzf by Molmil
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant
Descriptor: GLYCEROL, Nuclear receptor subfamily 4 group A member 1
Authors:Li, F, Tian, X, Li, A, Li, L, Liu, Y, Chen, H, Wu, Q, Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RZG
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BU of 4rzg by Molmil
Crystal Structure Analysis of the DNPA-bounded NUR77 Ligand binding Domain
Descriptor: GLYCEROL, Nuclear receptor subfamily 4 group A member 1, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate
Authors:Li, F, Tian, X, Li, A, Li, L, Liu, Y, Chen, H, Wu, Q, Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RE8
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BU of 4re8 by Molmil
Crystal Structure of TR3 LBD in complex with Molecule 5
Descriptor: 1-(3,4,5-trihydroxyphenyl)dodecan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
Authors:Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Weijia, W, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W.
Deposit date:2014-09-22
Release date:2015-09-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
4REF
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BU of 4ref by Molmil
Crystal Structure of TR3 LBD_L449W in complex with Molecule 2
Descriptor: 1-(3,4,5-trihydroxyphenyl)hexan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
Authors:Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W.
Deposit date:2014-09-22
Release date:2015-09-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
4REE
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BU of 4ree by Molmil
Crystal Structure of TR3 LBD in complex with Molecule 6
Descriptor: 1-(2,3,4-trihydroxyphenyl)nonan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
Authors:Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W.
Deposit date:2014-09-22
Release date:2015-09-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015

 

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