3RV5

Crystal structure of human cardiac troponin C regulatory domain in complex with cadmium and deoxycholic acid

Summary for 3RV5

Entry DOI	10.2210/pdb3rv5/pdb
Related	1AP4 1J1D 1LXF 1MXL 1SPY 1WRK
Descriptor	Troponin C, slow skeletal and cardiac muscles, CADMIUM ION, (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ... (5 entities in total)
Functional Keywords	helix-loop-helix ef-hand motif, metal ion coordination, calcium sensor, contractile protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	46038.00
Authors	Li, A.Y.,Lee, J.,Borek, D.,Otwinowski, Z.,Tibbits, G.,Paetzel, M. (deposition date: 2011-05-06, release date: 2011-08-31, Last modification date: 2011-11-16)
Primary citation	Li, A.Y.,Lee, J.,Borek, D.,Otwinowski, Z.,Tibbits, G.F.,Paetzel, M. Crystal structure of cardiac troponin C regulatory domain in complex with cadmium and deoxycholic Acid reveals novel conformation. J.Mol.Biol., 413:699-711, 2011 Cited by PubMed: 21920370 DOI: 10.1016/j.jmb.2011.08.049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation