3RV5
Crystal structure of human cardiac troponin C regulatory domain in complex with cadmium and deoxycholic acid
Summary for 3RV5
Entry DOI | 10.2210/pdb3rv5/pdb |
Related | 1AP4 1J1D 1LXF 1MXL 1SPY 1WRK |
Descriptor | Troponin C, slow skeletal and cardiac muscles, CADMIUM ION, (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ... (5 entities in total) |
Functional Keywords | helix-loop-helix ef-hand motif, metal ion coordination, calcium sensor, contractile protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 46038.00 |
Authors | Li, A.Y.,Lee, J.,Borek, D.,Otwinowski, Z.,Tibbits, G.,Paetzel, M. (deposition date: 2011-05-06, release date: 2011-08-31, Last modification date: 2011-11-16) |
Primary citation | Li, A.Y.,Lee, J.,Borek, D.,Otwinowski, Z.,Tibbits, G.F.,Paetzel, M. Crystal structure of cardiac troponin C regulatory domain in complex with cadmium and deoxycholic Acid reveals novel conformation. J.Mol.Biol., 413:699-711, 2011 Cited by PubMed: 21920370DOI: 10.1016/j.jmb.2011.08.049 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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