4RZF

Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant

Summary for 4RZF

• Entry DOI: 10.2210/pdb4rzf/pdb
• Related: 4RZE 4RZG
• Descriptor: Nuclear receptor subfamily 4 group A member 1, GLYCEROL (3 entities in total)
• Functional Keywords: transcription
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P22736
• Total number of polymer chains: 2
• Total formula weight: 57702.77

Authors

Li, F.,Tian, X.,Li, A.,Li, L.,Liu, Y.,Chen, H.,Wu, Q.,Lin, T. (deposition date: 2014-12-21, release date: 2015-03-18, Last modification date: 2024-02-28)

• Primary citation: Li, L.,Liu, Y.,Chen, H.Z.,Li, F.W.,Wu, J.F.,Zhang, H.K.,He, J.P.,Xing, Y.Z.,Chen, Y.,Wang, W.J.,Tian, X.Y.,Li, A.Z.,Zhang, Q.,Huang, P.Q.,Han, J.,Lin, T.,Wu, Q.; Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.; Nat.Chem.Biol., 11:339-346, 2015; PubMed: 25822914; DOI: 10.1038/nchembio.1788

Experimental method

X-RAY DIFFRACTION (1.99 Å)