4RZG
Crystal Structure Analysis of the DNPA-bounded NUR77 Ligand binding Domain
Summary for 4RZG
Entry DOI | 10.2210/pdb4rzg/pdb |
Related | 4RZE 4RZF |
Descriptor | Nuclear receptor subfamily 4 group A member 1, GLYCEROL, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate, ... (4 entities in total) |
Functional Keywords | nur77-lbd and dnpa complex, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P22736 |
Total number of polymer chains | 2 |
Total formula weight | 57883.01 |
Authors | |
Primary citation | Li, L.,Liu, Y.,Chen, H.Z.,Li, F.W.,Wu, J.F.,Zhang, H.K.,He, J.P.,Xing, Y.Z.,Chen, Y.,Wang, W.J.,Tian, X.Y.,Li, A.Z.,Zhang, Q.,Huang, P.Q.,Han, J.,Lin, T.,Wu, Q. Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat.Chem.Biol., 11:339-346, 2015 Cited by PubMed: 25822914DOI: 10.1038/nchembio.1788 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report