5WER
Crystal Structure of TAPBPR and H2-Dd complex
Summary for 5WER
Entry DOI | 10.2210/pdb5wer/pdb |
Related | 5MES |
Descriptor | H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, TAP binding protein related, ... (7 entities in total) |
Functional Keywords | antigen presentation, peptide editing, major histompatibility complex class i, mhc-i, tapasin, peptide loading complex, plc, immune response, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 12 |
Total formula weight | 346591.12 |
Authors | Jiang, J.S.,Natarajan, K.,Boyd, L.F.,Margulies, D.H. (deposition date: 2017-07-10, release date: 2017-10-18, Last modification date: 2019-08-28) |
Primary citation | Jiang, J.,Natarajan, K.,Boyd, L.F.,Morozov, G.I.,Mage, M.G.,Margulies, D.H. Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358:1064-1068, 2017 Cited by PubMed: 29025991DOI: 10.1126/science.aao5154 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.412 Å) |
Structure validation
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