5WKI

Crystal structure of PG90 TCR-CD1b-PG complex

Summary for 5WKI

• Entry DOI: 10.2210/pdb5wki/pdb
• Descriptor: T-cell surface glycoprotein CD1b, (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate, ACETATE ION, ... (13 entities in total)
• Functional Keywords: antigen presenting molecule, pg, phospholipid, mhc, cd1b, pg90, t-cell receptor, tcr, autoreactive, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 99162.39

Authors

Shahine, A.,Gras, S.,Rossjohn, J. (deposition date: 2017-07-25, release date: 2017-11-01, Last modification date: 2020-07-29)

• Primary citation: Shahine, A.,Van Rhijn, I.,Cheng, T.Y.,Iwany, S.,Gras, S.,Moody, D.B.,Rossjohn, J.; A molecular basis of human T cell receptor autoreactivity toward self-phospholipids.; Sci Immunol, 2:-, 2017; PubMed: 29054999; DOI: 10.1126/sciimmunol.aao1384

Experimental method

X-RAY DIFFRACTION (2.75 Å)