3QO4
| The Crystal Structure of Death Receptor 6 | Descriptor: | ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21 | Authors: | Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E. | Deposit date: | 2011-02-09 | Release date: | 2011-05-18 | Last modified: | 2012-02-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP). J.Mol.Biol., 409, 2011
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3THM
| Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ... | Authors: | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | Deposit date: | 2011-08-19 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell Death Differ., 19, 2012
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3U3Q
| The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2013-07-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS. Acta Crystallogr.,Sect.D, 68, 2012
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3U3S
| The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2013-07-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS. Acta Crystallogr.,Sect.D, 68, 2012
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3U3T
| The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2012-07-11 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS Acta Crystallogr.,Sect.D, 68, 2012
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3TJE
| Crystal structure of Fas receptor extracellular domain in complex with Fab E09 | Descriptor: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | Authors: | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | Deposit date: | 2011-08-24 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell Death Differ., 19, 2012
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3U3P
| The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2013-07-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS Acta Crystallogr.,Sect.D, 68, 2012
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3U3V
| The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2012-07-11 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS Acta Crystallogr.,Sect.D, 68, 2012
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5L36
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1JMA
| CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE CELLULAR RECEPTOR HVEA/HVEM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN D, HERPESVIRUS ENTRY MEDIATOR, ... | Authors: | Carfi, A, Willis, S.H, Whitbeck, J.C, Krummenacker, C, Cohen, G.H, Eisenberg, R.J, Wiley, D.C. | Deposit date: | 2001-07-17 | Release date: | 2001-09-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Herpes simplex virus glycoprotein D bound to the human receptor HveA. Mol.Cell, 8, 2001
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4YN0
| Crystal structure of APP E2 domain in complex with DR6 CRD domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amyloid beta A4 protein, MAGNESIUM ION, ... | Authors: | Xu, K, Nikolov, D. | Deposit date: | 2015-03-08 | Release date: | 2015-04-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation. Genes Dev., 29, 2015
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4E4D
| Crystal structure of mouse RANKL-OPG complex | Descriptor: | CHLORIDE ION, Tumor necrosis factor ligand superfamily member 11, soluble form, ... | Authors: | Nelson, C.A, Fremont, D.H. | Deposit date: | 2012-03-12 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor. Structure, 20, 2012
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7MSG
| The crystal structure of LIGHT in complex with HVEM and CD160 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD160 antigen, soluble form,Tumor necrosis factor receptor superfamily member 14, ... | Authors: | Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C. | Deposit date: | 2021-05-11 | Release date: | 2021-10-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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5BNQ
| Crystal structure of hRANKL-mRANK complex | Descriptor: | CHLORIDE ION, PHOSPHATE ION, SODIUM ION, ... | Authors: | Ren, J. | Deposit date: | 2015-05-26 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis. Sci Rep, 5, 2015
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3IJ2
| Ligand-receptor structure | Descriptor: | Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16) | Authors: | Feng, D, Garcia, K.C. | Deposit date: | 2009-08-03 | Release date: | 2010-01-12 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | Molecular and structural insight into proNGF engagement of p75NTR and sortilin. J.Mol.Biol., 396, 2010
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8HLB
| Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2 | Descriptor: | TR109 heavy chain, TR109 light chain, TR92 heavy chain, ... | Authors: | Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K. | Deposit date: | 2022-11-29 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection. Commun Biol, 6, 2023
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1SG1
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3K51
| Crystal Structure of DcR3-TL1A complex | Descriptor: | Decoy receptor 3, Tumor necrosis factor ligand superfamily member 15, secreted form | Authors: | Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | Deposit date: | 2009-10-06 | Release date: | 2010-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Decoy Strategies: The Structure of TL1A:DcR3 Complex. Structure, 19, 2011
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1D4V
| Crystal structure of trail-DR5 complex | Descriptor: | DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND | Authors: | Mongkolsapaya, J, Grimes, J.M, Stuart, D.I, Jones, E.Y, Screaton, G.R. | Deposit date: | 1999-10-06 | Release date: | 1999-11-01 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation Nat.Struct.Biol., 6, 1999
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3BUK
| Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotrophin-3, Tumor necrosis factor receptor superfamily member 16 | Authors: | Jiang, T, Gong, Y, Cao, P, Yu, H.J. | Deposit date: | 2008-01-02 | Release date: | 2008-07-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. Nature, 454, 2008
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5CIR
| Crystal structure of death receptor 4 (DR4; TNFFRSF10A) bound to TRAIL (TNFSF10) | Descriptor: | CHLORIDE ION, Tumor necrosis factor ligand superfamily member 10, Tumor necrosis factor receptor superfamily member 10A, ... | Authors: | Sheriff, S. | Deposit date: | 2015-07-13 | Release date: | 2017-01-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex. Acta Crystallogr F Struct Biol Commun, 71, 2015
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1TNR
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4RSU
| Crystal structure of the light and hvem complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | Authors: | Liu, W, Ramagoal, U.A, Himmel, D, Bonanno, J.B, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-11-11 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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1D0G
| CRYSTAL STRUCTURE OF DEATH RECEPTOR 5 (DR5) BOUND TO APO2L/TRAIL | Descriptor: | APOPTOSIS-2 LIGAND, CHLORIDE ION, DEATH RECEPTOR-5, ... | Authors: | Hymowitz, S.G, Christinger, H.W, Fuh, G, O'Connell, M.P, Kelley, R.F, Ashkenazi, A, de Vos, A.M. | Deposit date: | 1999-09-09 | Release date: | 1999-10-22 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5. Mol.Cell, 4, 1999
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3ALQ
| Crystal structure of TNF-TNFR2 complex | Descriptor: | COBALT (II) ION, Tumor necrosis factor, Tumor necrosis factor receptor superfamily member 1B | Authors: | Mukai, Y, Nakamura, T, Yamagata, Y, Tsutsumi, Y. | Deposit date: | 2010-08-06 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Solution of the Structure of the TNF-TNFR2 Complex Sci.Signal., 3, 2010
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